Showing results 1 to 4 of 4
Issue Date | Title | Author(s) |
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2017-12 | CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide | Moutal, Aubin; Yang, Xiaofang; Li, Wennan; Gilbraith, Kerry B.; Luo, Shizhen; Cai, Song; Francois-Moutal, Liberty; Chew, Lindsey A.; Yeon, Seul Ki; Bellampalli, Shreya S.; Qu, Chaoling; Xie, Jennifer Y.; Ibrahim, Mohab M.; Khanna, May; Park, Ki Duk; Porreca, Frank; Khanna, Rajesh |
2016-04 | (S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5 | Moutal, Aubin; Francois-Moutal, Liberty; Perez-Miller, Samantha; Cottier, Karissa; Chew, Lindsey Anne; Yeon, Seul Ki; Dai, Jixun; Park, Ki Duk; Khanna, May; Khanna, Rajesh |
2016-07 | (S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology | Moutal, Aubin; Chew, Lindsey A.; Yang, Xiaofang; Wang, Yue; Yeon, Seul Ki; Telemi, Edwin; Meroueh, Seeneen; Park, Ki Duk; Shrinivasan, Raghuraman; Gilbraith, Kerry B.; Qu, Chaoling; Xie, Jennifer Y.; Patwardhan, Amol; Vanderah, Todd W.; Khanna, May; Porreca, Frank; Khanna, Rajesh |
2019-07 | Targeting the CaV alpha-CaV beta interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy | Khanna, Rajesh; Yu, Jie; Yang, Xiaofang; Moutal, Aubin; Chefdeville, Aude; Gokhale, Vijay; Shuja, Zunaira; Chew, Lindsey A.; Bellampalli, Shreya S.; Luo, Shizhen; Francois-Moutal, Liberty; Serafini, Maria J.; Ha, Taehwan; Perez-Miller, Samantha; Park, Ki Duk; Patwardhan, Amol M.; Streicher, John M.; Colecraf, Henry M.; Khanna, May |