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Showing results 1 to 12 of 12

Issue DateTitleAuthor(s)
2013-07-25(Biphenyl-4-yl)methylammonium Chlorides: Potent Anticonvulsants That Modulate Na+ CurrentsLee, Hyosung; Park, Ki Duk; Yang, Xiao-Fang; Dustrude, Erik T.; Wilson, Sarah M.; Khanna, Rajesh; Kohn, Harold
2015-02Chimeric Agents Derived from the Functionalized Amino Acid, Lacosamide, and the alpha-Aminoamide, Safinamide: Evaluation of Their Inhibitory Actions on Voltage-Gated Sodium Channels, and Antiseizure and Antinociception Activities and Comparison with Lacosamide and SafinamidePark, Ki Duk; Yang, Xiao-Fang; Dustrude, Erik T.; Wang, Yuying; Ripsch, Matthew S.; White, Fletcher A.; Khanna, Rajesh; Kohn, Harold
2017-12CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-LacosamideMoutal, Aubin; Yang, Xiaofang; Li, Wennan; Gilbraith, Kerry B.; Luo, Shizhen; Cai, Song; Francois-Moutal, Liberty; Chew, Lindsey A.; Yeon, Seul Ki; Bellampalli, Shreya S.; Qu, Chaoling; Xie, Jennifer Y.; Ibrahim, Mohab M.; Khanna, May; Park, Ki Duk; Porreca, Frank; Khanna, Rajesh
2018-05CRMP2 Phosphorylation Drives Glioblastoma Cell ProliferationMoutal, Aubin; Villa, Lex Salas; Yeon, Seul Ki; Householder, Kyle T.; Park, Ki Duk; Sirianni, Rachael W.; Khanna, Rajesh
2014-05-28Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3 beta and CDK5 following traumatic brain injuryWilson, Sarah M.; Yeon, Seul Ki; Yang, Xiao-Fang; Park, Ki Duk; Khanna, Rajesh
2013-03Discovery of Lacosamide Affinity Bait Agents That Exhibit Potent Voltage-Gated Sodium Channel Blocking PropertiesPark, Ki Duk; Yang, Xiao-Fang; Lee, Hyosung; Dustrude, Erik T.; Wang, Yuying; Khanna, Rajesh; Kohn, Harold
2022-12Neuronal CRMP2 phosphorylation inhibition by the flavonoid, naringenin, contributes to the reversal of spinal sensitization and arthritic pain improvementJiang, Yue-Peng; Wang, Song; Lai, Wei-Dong; Wu, Xue-Qing; Jin, Yan; Xu, Zheng-Hao; Moutal, Aubin; Khanna, Rajesh; Park, Ki Duk; Shan, Zhi-Ming; Wen, Cheng-Ping; Yu, Jie
2019-07Phosphorylated CRMP2 Regulates Spinal Nociceptive NeurotransmissionYu, Jie; Moutal, Aubin; Dorame, Angie; Bellampalli, Shreya S.; Chefdeville, Aude; Kanazawa, Iori; Pham, Nancy Y. N.; Park, Ki Duk; Weimer, Jill M.; Khanna, Rajesh
2016-04(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5Moutal, Aubin; Francois-Moutal, Liberty; Perez-Miller, Samantha; Cottier, Karissa; Chew, Lindsey Anne; Yeon, Seul Ki; Dai, Jixun; Park, Ki Duk; Khanna, May; Khanna, Rajesh
2016-07(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacologyMoutal, Aubin; Chew, Lindsey A.; Yang, Xiaofang; Wang, Yue; Yeon, Seul Ki; Telemi, Edwin; Meroueh, Seeneen; Park, Ki Duk; Shrinivasan, Raghuraman; Gilbraith, Kerry B.; Qu, Chaoling; Xie, Jennifer Y.; Patwardhan, Amol; Vanderah, Todd W.; Khanna, May; Porreca, Frank; Khanna, Rajesh
2014-07-24Substituted N-(Biphenyl-4 '-yl)methyl (R)-2-Acetamido-3-methoxypropionamides: Potent Anticonvulsants That Affect Frequency (Use) Dependence and Slow Inactivation of Sodium ChannelsLee, Hyosung; Park, Ki Duk; Torregrosa, Robert; Yang, Xiao-Fang; Dustrude, Erik T.; Wang, Yuying; Wilson, Sarah M.; Barbosa, Cindy; Xiao, Yucheng; Cummins, Theodore R.; Khanna, Rajesh; Kohn, Harold
2019-07Targeting the CaV alpha-CaV beta interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacyKhanna, Rajesh; Yu, Jie; Yang, Xiaofang; Moutal, Aubin; Chefdeville, Aude; Gokhale, Vijay; Shuja, Zunaira; Chew, Lindsey A.; Bellampalli, Shreya S.; Luo, Shizhen; Francois-Moutal, Liberty; Serafini, Maria J.; Ha, Taehwan; Perez-Miller, Samantha; Park, Ki Duk; Patwardhan, Amol M.; Streicher, John M.; Colecraf, Henry M.; Khanna, May
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