Showing results 1 to 23 of 23
Issue Date | Title | Author(s) |
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2020-01-01 | A novel chalcone derivative as Nrf2 activator attenuates learning and memory impairment in a scopolamine-induced mouse model | Kim, Hyeon Jeong; Jang, Bo Ko; Park, Jong-Hyun; Choi, Ji Won; Park, Sun Jun; Byeon, Seong Rim; Pae, Ae Nim; Lee, Yang Sup; Cheong, Eunji; Park, Ki Duk |
2019-07 | Antioxidant, Anti-inflammatory, and Neuroprotective Effects of Novel Vinyl Sulfonate Compounds as Nrf2 Activator | Choi, Ji Won; Shin, Su Jeong; Kim, Hyeon Ji; Park, Jong-Hyun; Kim, Hyeon Jeong; Lee, Elijah Hwejin; Pae, Ae Nim; Bahn, Yong Sun; Park, Ki Duk |
2021-02-15 | Development and optimization of halogenated vinyl sulfones as Nrf2 activators for the treatment of Parkinson's disease | Choi, Ji Won; Kim, Siwon; Yoo, Jong Seok; Kim, Hyeon Jeong; Kim, Hyeon Ji; Kim, Byung Eun; Lee, Elijah Hwejin; Lee, Yong Sup; Park, Jong-Hyun; Park, Ki Duk |
2024-10 | Discovery and Optimization of a Series of Vinyl Sulfoximine-Based Analogues as Potent Nrf2 Activators for the Treatment of Multiple Sclerosis | Kim, Yoowon; Kim, Jaehwan; Kim, Byungeun; Kim, Rium; Kim, Hyeon Jeong; Lee, Elijah Hwejin; Kim, Jushin; Park, Jiwoo; Jeong, Yeeun; Park, Sang In; Kim, Hyemin; Kang, Minsik; Lee, Jaeick; Bahn, Yong-Sun; Choi, Ji Won; Park, Jong-Hyun; Park, Ki Duk |
2021-11 | Discovery of 3,4-dichloro-N-(1H-indol-5-yl)benzamide: A highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability and action | Elkamhawy, Ahmed; Kim, Hyeon Jeong; Elsherbeny, Mohamed H.; Paik, Sora; Park, Jong-Hyun; Gotina, Lizaveta; Abdellattif, Magda H.; Gouda, Noha A.; Cho, Jungsook; Lee, Kyeong; Pae, Ae Nim; Park, Ki Duk; Roh, Eun Joo |
2020-01 | Discovery of N-(1-(3-fluorobenzoyl)-1H-indol-5-yl)pyrazine-2-carboxamide: a novel, selective, and competitive indole-based lead inhibitor for human monoamine oxidase B | Elkamhawy, Ahmed; Paik, Sora; Kim, Hyeon Jeong; Park, Jong-Hyun; Londhe, Ashwini M.; Lee, Kyeong; Pae, Ae Nim; Park, Ki Duk; Roh, Eun Joo |
2022-02 | Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis | Park, Sun Jun; Yeon, Seul Ki; Yoowon Kim; Kim, Hyeon Jeong; KIm Si Won; KIM, JU SHIN; Choi, Ji Won; Byung, Eun Kim; Elijah, Hwejin Lee; Kim Ri-um; SEO, SEON HEE; Lee, Jae Ick; Jun Woo Kim; Ha-Yeon Lee; Hayoung Hwang; Yong-Sun Bahn; Eunji Cheong; Park, Jong Hyun; Park, Ki Duk |
2023-08 | Exploration of Tetrahydroisoquinoline- and Benzo[c]azepine-Based Sphingosine 1-Phosphate Receptor 1 Agonists for the Treatment of Multiple Sclerosis | Cha, Eunji; Kim, Jushin; Gotina, Lizaveta; Kim, Jaehwan; Kim, Hyeon Jeong; Seo, Seon Hee; Park, Jeong-Eun; Joo, Jeongmin; Kang, Minsik; Lee, Jaeick; Hwang, Hayoung; Kim, Hak Joong; Pae, Ae Nim; Park, Ki Duk; Park, Jong-Hyun; Lim, Sang Min |
2024-09 | Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease | Kim, Hyeon Jeong; Kim, Haelee; Song, Jaeyoung; Hong, Jun Young; Lee, Elijah Hwejin; Londhe, Ashwini M; Choi, Ji Won; Park, Sun Jun; Oh, Eunseok; Yoon, Heeseok; Hwang, Hoosang; Hahn, Dongyup; Jung, Kyungjin; Kwon, Sugyeong; Kadayat, Tara Man; Ma, Min Jung; Joo, Jeongmin; Kim, Jina; Bae, Jae Hyun; Hwang, Hayoung; Pae, Ae Nim; Cho, Sung Jin; Park, Jong Hyun; Chin, Jungwook; Kang, Heonjoong; Park, Ki Duk |
2020-12 | Identification and evaluation of a napyradiomycin as a potent Nrf2 activator: Anti-oxidative and anti-inflammatory activities | Choi, Ji Won; Kim, Geum Jin; Kim, Hyeon Jeong; Nam, Joo-Won; Kim, Jushin; Chin, Jungwook; Park, Jong-Hyun; Choi, Hyukjae; Park, Ki Duk |
2021-07 | KDS2010, a Newly Developed Reversible MAO-B Inhibitor, as an Effective Therapeutic Candidate for Parkinson's Disease | Nam, Min-Ho; Park, Jong-Hyun; Song, Hyo jung; Choi, Ji Won; Kim, Siwon; 장보고; Yoon, Hyung Ho; Heo, Jun Young; Lee, Hyowon; An, Heeyoung; Kim, Hyeon Jeong; Park, Sun Jun; Cho, Doo-Wan; Yang, Young-Su; Han, Su-Cheol; Kim, Sangwook; Oh, Soo-Jin; Jeon, Sang Ryong; Park, Ki Duk; Lee, C. Justin |
2019-03 | Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer's disease | Park, Jong-Hyun; Ju, Yeon Ha; Choi, Ji Won; Song, Hyo Jung; Jang, Bo Ko; Woo, Junsung; Chun, Heejung; Kim, Hyeon Jeong; Shin, Su Jeong; Yarishkin, Oleg; Jo, Seonmi; Park, Mijeong; Yeon, Seul Ki; Kim, Siwon; Kim, Jeongyeon; Nam, Min-Ho; Londhe, Ashwini M.; Kim, Jina; Cho, Sung Jin; Cho, Suengmok; Lee, Changho; Hwang, Sung Yeoun; Kim, Sang Wook; Oh, Soo-Jin; Cho, Jeiwon; Pae, Ae Nim; Lee, C. Justin; Park, Ki Duk |
2020-05 | Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal model | Kim, Siwon; Viswanath, Ambily Nath Indu; Park, Jong-Hyun; Lee, Ha Eun; Park, A. Yeong; Choi, Ji Won; Kim, Hyeon Jeong; Londhe, Ashwini M.; Jang, Bo Ko; Lee, Jaeick; Hwang, Hayoung; Lim, Sang Min; Pae, Ae Nim; Park, Ki Duk |
2021-11-11 | Optimization and Evaluation of Novel Antifungal Agents for the Treatment of Fungal Infection | Choi, Ji Won; Lee, Kyung-Tae; Kim, Siwon; Lee, Ye Rim; Kim, Hyeon Ji; Seo, Kyung Jin; Lee, Myung Ha; Yeon, Seul Ki; Jang, Bo Ko; Park, Sun Jun; Kim, Hyeon Jeong; Park, Jong-Hyun; Kim, Dahee; Lee, Dong-Gi; Cheong, Eunji; Lee, Jong-Seung; Bahn, Yong-Sun; Park, Ki Duk |
2023-08 | Optimization and evaluation of pyridinyl vinyl sulfones as Nrf2 activator for the antioxidant and anti-inflammatory effects | Kim, Byungeun; Kim, Rium; Kim, Hyeon Jeong; Kim, Yoowon; Park, Sun Jun; Lee, Elijah Hwejin; Kim, Jushin; Kim, Jaehwan; Choi, Ji Won; Park, Jong-Hyun; Park, Ki Duk |
2019-01 | Optimization of Vinyl Sulfone Derivatives as Potent Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Activators for Parkinson's Disease Therapy | Choi, Ji Won; Kim, Siwon; Park, Jong-Hyun; Kim, Hyeon Jeong; Shin, Su Jeon; Kim, Jin Woo; Woo, Seo Yeon; Lee, Changho; Han, Sang Moon; Lee, Jaeick; Pae, Ae Nim; Han, Gyoonhee; Park, Ki Duk |
2024-09 | Phloroglucinol Derivatives Exert Anti-Inflammatory Effects and Attenuate Cognitive Impairment in LPS-Induced Mouse Model | Kim, Jushin; Choi, Ji Won; Kim, Hyeon Jeong; Kim, Byungeun; Kim, Yoowon; Lee, Elijah Hwejin; Kim, Rium; Kim, Jaehwan; Park, Jiwoo; Jeong, Yeeun; Park, Jong-Hyun; Park, Ki Duk |
2022-12 | Positional scanning of natural product hispidol's ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases | Hassan, Ahmed H. E.; Kim, Hyeon Jeong; Gee, Min Sung; Park, Jong-Hyun; Jeon, Hye Rim; Lee, Cheol Jung; Choi, Yeonwoo; Moon, Suyeon; Lee, Danbi; Lee, Jong Kil; Park, Ki Duk; Lee, Yong Sup |
2023-05 | Synthesis and Biological Evaluation of O-6-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative Diseases | Hassan, Ahmed H. E.; Kim, Hyeon Jeong; Park, Keontae; Choi, Yeonwoo; Moon, Suyeon; Lee, Chae Hyeon; Kim, Yeon Ju; Cho, Soo Bin; Gee, Min Sung; Lee, Danbi; Park, Jong-Hyun; Lee, Jong Kil; Ryu, Jong Hoon; Park, Ki Duk; Lee, Yong Sup |
2024-08 | Synthesis and biological evaluation of O4′-benzyl-hispidol derivatives and analogs as dual monoamine oxidase-B inhibitors and anti-neuroinflammatory agents | Hassan, Ahmed H. E.; Choi, Yeonwoo; Kim, Rium; Kim, Hyeon Jeong; Almatary, Aya M.; El-Sayed, Selwan M.; Lee, Yeongae; Lee, Jong Kil; Park, Ki Duk; Lee, Yong Sup |
2018-11-01 | Synthesis and Development of Novel Compounds Selectively Targeting on Sphingosine 1-Phosphate Receptor 1 (S1P1) for Treatment of Multiple Sclerosis | Yeon, Seul Ki; Park, Jong-Hyun; Park, Ki Duk; Kim, Hyeon Jeong; Shin, Su Jeong |
2018-01-01 | Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy | Yeon, Seul Ki; Choi, Ji Won; Park, Jong-Hyun; Lee, Ye Rim; Kim, Hyeon Jeong; Shin, Su Jeong; Jang, Bo Ko; Kim, Siwon; Bahn, Yong-Sun; Han, Gyoonhee; Lee, Yong Sup; Pae, Ae Nim; Park, Ki Duk |
2022-05 | Synthesis and Evaluation of Serinolamide Derivatives as Sphingosine-1-Phosphate-1 (S1P(1)) Receptor Agonists | Park, Sun Jun; Kim, Jushin; Kim, Jaehwan; Kim, Yoowon; Lee, Elijah Hwejin; Kim, Hyeon Jeong; Kim, Siwon; Kim, Byungeun; Kim, Rium; Choi, Ji Won; Park, Jong-Hyun; Park, Ki Duk |