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Showing results 1 to 30 of 31

Issue DateTitleAuthor(s)
2017-10A Difluoroboron beta-Diketonate Probe Shows "Turn-on" Near-Infrared Fluorescence Specific for Tau FibrilsPark, Kwang-su; Kim, Mi Kyoung; Seo, Yujin; Ha, Taewoong; Yoo, Kyeongha; Hyeon, Seung Jae; Hwang, Yu Jin; Lee, Junghee; Ryu, Hoon; Choo, Hyunah; Chong, Youhoon
2016-11A Smart Near-Infrared Fluorescence Probe for Selective Detection of Tau Fibrils in Alzheimer's DiseaseSeo, Yujin; Park, Kwang-su; Ha, Taewoong; Kim, Mi Kyoung; Hwang, Yu Jin; Lee, Junghee; Ryu, Hoon; Choo, Hyunah; Chong, Youhoon
2020-01Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson's DiseaseHeo, Jun Young; Nam, Min-Ho; Yoon, Hyung Ho; Kim, Jeongyeon; Hwang, Yu Jin; Won, Woojin; Woo, Dong Ho; Lee, Ji Ae; Park, Hyun-Jung; Jo, Seonmi; Lee, Min Joung; Kim, Sunpil; Shim, Jeong-Eun; Jang, Dong-Pyo; Kim, Kyoung I.; Huh, Sue H.; Jeong, Jae Y.; Kowall, Neil W.; Lee, Junghee; Im, Hyeonjoo; Park, Jong Hyun; Jang, Bo Ko; Park, Ki Duk; Lee, Hyunjoo J.; Shin, Hyogeun; Cho, Il-Joo; Hwang, Eun Mi; Kim, YoungSoo; Kim, Hye Yun; Oh, Soo-Jin; Lee, Seung Eun; Paek, Sun Ha; Yoon, Jong Hyuk; Jin, Byung K.; Kweon, Gi Ryang; Shim, Insop; Hwang, Onyou; Ryu, Hoon; Jeon, Sang Ryong; Lee, C. Justin
2020-06-01Alterations of transcriptome signatures in head trauma-related neurodegenerative disordersCho, Hyesun; Hyeon, Seung Jae; Shin, Jong-Yeon; Alvarez, Victor E.; Stein, Thor D.; Lee, Junghee; Kowall, Neil W.; McKee, Ann C.; Ryu, Hoon; Seo, Jeong-Sun
2016-10Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALSLee, Junghee; Hyeon, Seung Jae; Im, Hyeonjoo; Ryu, Hyun; Kim, Yunha; Ryu, Hoon
2024-07Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in Alzheimer's diseaseKim, Suhyun; Chun, Heejung; Kim, Yunha; Kim, Yeyun; Park, Uiyeol; Chu, Jiyeon; Bhalla, Mridula; Choi, Seung-Hye; Yousefian-Jazi, Ali; Kim, Sojung; Hyeon, Seung Jae; Kim, Seungchan; Kim, Yeonseo; Ju, Yeon Ha; Lee, Seung Eun; Lee, Hyunbeom; Lee, Kyungeun; Oh, Soo-Jin; Hwang, Eun Mi; Lee, Junghee; Lee, C. Justin; Ryu, Hoon
2022-08Astrocytic urea cycle detoxifies A beta-derived ammonia while impairing memory in Alzheimer's diseaseJu, Yeon Ha; Bhalla, Mridula; Hyeon, Seung Jae; Oh, Ju Eun; Yoo, Seonguk; Chae, Uikyu; Kwon, Jea; Koh, Wuhyun; Lim, Jiwoon; Park, Yongmin Mason; Lee, Junghee; Cho, Il-Joo; Lee, Hyunbeom; Ryu, Hoon; Lee, C. Justin
2023-10Crif1 deficiency in dopamine neurons triggers early-onset parkinsonismHeo, Jun Young; Park, Ah Hyung; Lee, Min Joung; Ryu, Min Jeong; Kim, Yong Kyung; Jang, Yun Seon; Kim, Soo Jeong; Shin, So Yeon; Son, Hyo Jin; Stein, Thor D; Huh, Yang Hoon; Chung Sookja K; Choi, Song Yi; Kim, Jin Man; Hwang, Onyou; Shong, Minho; Hyeon, Seung Jae; Lee, Junghee; Ryu, Hoon; Kim, Daesoo; Kwen, Gi Ryang
2022-09Decreased FAK activity and focal adhesion dynamics impair proper neurite formation of medium spiny neurons in Huntington's diseaseLee, Hae Nim; Hyeon, Seung Jae; Kim, Heejung; Sim, Kyoung Mi; Kim, Yunha; Ju, Jeongmin; Lee, Junghee; Wang, Yingxiao; Ryu, Hoon; Seong, Jihye
2021-09Dysfunction of X-linked inhibitor of apoptosis protein (XIAP) triggers neuropathological processes via altered p53 activity in Huntington's diseaseHyeon, Seung Jae; Park, Jinyoung; Yoo, Junsang; Kim, Su-Hyun; Hwang, Yu Jin; Kim, Seung-Chan; Liu, Tian; Shim, Hyun Soo; Kim, Yunha; Cho, Yakdol; Woo, Jiwan; Kim, Key-Sun; Myers, Richard H.; Ryu, Hannah L.; Kowall, Neil W.; Song, Eun Joo; Hwang, Eun Mi; Seo, Hyemyung; Lee, Junghee; Ryu, Hoon
2014-03Epigenetic Mechanisms of Rubinstein-Taybi SyndromePark, Elizabeth; Kim, Yunha; Ryu, Hyun; Kowall, Neil W.; Lee, Junghee; Ryu, Hoon
2013-05Epigenetic regulation of cholinergic receptor M1 (CHRM1) by histone H3K9me3 impairs Ca2+ signaling in Huntington's diseaseLee, Junghee; Hwang, Yu Jin; Shin, Jong-Yeon; Lee, Won-Chul; Wie, Jinhong; Kim, Ki Yoon; Lee, Min Young; Hwang, Daehee; Ratan, Rajiv R.; Pae, Ae Nim; Kowall, Neil W.; So, Insuk; Kim, Jong-Il; Ryu, Hoon
2020-06Epigenome signatures landscaped by histone H3K9me3 are associated with the synaptic dysfunction in Alzheimer's diseaseLee, Min Young; Lee, Junghee; Hyeon, Seung Jae; Cho, Hyesun; Hwang, Yu Jin; Shin, Jong-Yeon; McKee, Ann C.; Kowall, Neil W.; Kim, Jong-Il; Stein, Thor D.; Hwang, Daehee; Ryu, Hoon
2014-02ESET methylates UBF at K232/254 and regulates nucleolar heterochromatin plasticity and rDNA transcriptionHwang, Yu Jin; Han, Dohyun; Kim, Ki Yoon; Min, Sun-Joon; Kowall, Neil W.; Yang, Liu; Lee, Junghee; Kim, Youngsoo; Ryu, Hoon
2019-07-01EWSR1, a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathwaysLee, Junghee; Nguyen, Phuong T.; Shim, Hyun Soo; Hyeon, Seung Jae; Im, Hyeonjoo; Choi, Mi-Hyun; Chung, Sooyoung; Kowall, Neil W.; Lee, Sean Bong; Ryu, Hoon
2018-04Genetic Ablation of EWS RNA Binding Protein 1 (EWSR1) Leads to Neuroanatomical Changes and Motor Dysfunction in MiceYoon, Yeojun; Park, Hasang; Kim, Sangyeon; Nguyen, Phuong T.; Hyeon, Seung Jae; Chung, Sooyoung; Im, Hyeonjoo; Lee, Junghee; Lee, Sean Bong; Ryu, Hoon
2020-11-17How Microglia Manages Non-cell Autonomous Vicious Cycling of A beta Toxicity in the Pathogenesis of ADSeol, YunHee; Ki, Soomin; Ryu, Hannah L.; Chung, Sooyoung; Lee, Junghee; Ryu, Hoon
2021-10Hypermethylation of Mest promoter causes aberrant Wnt signaling in patients with Alzheimer's diseasePrasad, Renuka; Jung, Hwajin; Tan, Anderson; Song, Yonghee; Moon, Sungho; Shaker, Mohammed R.; Sun, Woong; Lee, Junghee; Ryu, Hoon; Lim, Hyun Kook; Jho, Eek-hoon
2016-08Integrated analysis of omics data using microRNA-target mRNA network and PPI network reveals regulation of Gnai1 function in the spinal cord of Ews/Ewsr1 KO miceLee, Chai-Jin; Ahn, Hongryul; Lee, Sean Bong; Shin, Jong-Yeon; Park, Woong-Yang; Kim, Jong-Il; Lee, Junghee; Ryu, Hoon; Kim, Sun
2019-06Metabolomic Analysis Identifies Alterations of Amino Acid Metabolome Signatures in the Postmortem Brain of Alzheimer's DiseaseKim, Yoon Hwan; Shim, Hyun Soo; Kim, Kyoung Heon; Lee, Junghee; Chung, Bong Chul; Kowall, Neil W.; Ryu, Hoon; Lee, Jeongae
2015-07-31Modulation of autophagy by miRNAsKim, Yunha; Lee, Junghee; Ryu, Hoon
2022-12Modulation of histone H3K4 dimethylation by spermidine ameliorates motor neuron survival and neuropathology in a mouse model of ALSChoi, Seung-Hye; Yousefian-Jazi, Ali; Hyeon, Seung Jae; Nguyen, Phuong Thi Thanh; Chu, Jiyeon; Kim, Sojung; Kim, Suhyun; Ryu, Hannah L.; Kowall, Neil W.; Ryu, Hoon; Lee, Junghee
2022-07Non-Targeted Metabolomics Approach Revealed Significant Changes in Metabolic Pathways in Patients with Chronic Traumatic EncephalopathyLee, Jinkyung; Kim, Suhyun; Kim, Yoon Hwan; Park, Uiyeol; Lee, Junghee; McKee, Ann C.; Kim, Kyoung Heon; Ryu, Hoon; Lee, Jeongae
2014-06Nucleolar dysfunction in Huntington's diseaseLee, Junghee; Hwang, Yu Jin; Ryu, Hyun; Kowall, Neil W.; Ryu, Hoon
2020-12Pathogenic Genome Signatures That Damage Motor Neurons in Amyotrophic Lateral SclerosisYousefian-Jazi, Ali; Seol, YunHee; Kim, Jieun; Ryu, Hannah L.; Lee, Junghee; Ryu, Hoon
2021-02Power Failure of Mitochondria and Oxidative Stress in Neurodegeneration and Its Computational ModelsWoo, JunHyuk; Cho, Hyesun; Seol, YunHee; Kim, Soon Ho; Park, Chanhyeok; Yousefian-Jazi, Ali; Hyeon, Seung Jae; Lee, Junghee; Ryu, Hoon
2019-06Quantitative Proteomic Analysis Reveals Impaired Axonal Guidance Signaling in Human Postmortem Brain Tissues of Chronic Traumatic EncephalopathyBi, Baibin; Choi, Han-Pil; Hyeon, Seung Jae; Sun, Shengnan; Su, Ning; Liu, Yuguang; Lee, Junghee; Kowall, Neil W.; McKee, Ann C.; Yang, Jing-Hua; Ryu, Hoon
2017-11Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington's diseaseLee, Junghee; Hwang, Yu Jin; Kim, Yunha; Lee, Min Young; Hyeon, Seung Jae; Lee, Soojin; Kim, Dong Hyun; Jang, Sung Jae; Im, Hyoenjoo; Min, Sun-Joon; Choo, Hyunah; Pae, Ae Nim; Kim, Dong Jin; Cho, Kyung Sang; Kowall, Neil W.; Ryu, Hoon
2018-02SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's diseaseLee, Junghee; Kim, Yunha; Liu, Tian; Hwang, Yu Jin; Hyeon, Seung Jae; Im, Hyeonjoo; Lee, Kyungeun; Alvarez, Victor E.; McKee, Ann C.; Um, Soo-Jong; Hur, Manwook; Mook-Jung, Inhee; Kowall, Neil W.; Ryu, Hoon
2017-05Transcriptome analyses of chronic traumatic encephalopathy show alterations in protein phosphatase expression associated with tauopathySeo, Jeong-Sun; Lee, Seungbok; Shin, Jong-Yeon; Hwang, Yu Jin; Cho, Hyesun; Yoo, Seong-Keun; Kim, Yunha; Lim, Sung su; Kim, Yun Kyung; Hwang, Eun Mi; Kim, Su Hyun; Kim, Chong-Hyun; Hyeon, Seung Jae; Yun, Ji-Young; Kim, Jihye; Kim, Yona; Alvarez, Victor E.; Stein, Thor D.; Lee, Junghee; Kim, Dong Jin; Kim, Jong-Il; Kowall, Neil W.; Ryu, Hoon; McKee, Ann C.
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