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Showing results 1 to 26 of 26

Issue DateTitleAuthor(s)
2020-08-11Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomesChoi, Won Hoon; Yun, Yejin; Park, Seoyoung; Jeon, Jun Hyoung; Lee, Jeeyoung; Lee, Jung Hoon; Yang, Su-A; Kim, Nak-Kyoon; Jung, Chan Hoon; Kwon, Yong Tae; Han, Dohyun; Lim, Sang Min; Lee, Min Jae
2021-04-21CHIP-mediated hyperubiquitylation of tau promotes its self-assembly into the insoluble tau filamentsKim, Ji Hyeon; Lee, Jeeyoung; Choi, Won Hoon; Park, Seoyoung; Park, Seo Hyeong; Lee, Jung Hoon; Lim, Sang Min; Mun, Ji Young; Cho, Hyun-Soo; Han, Dohyun; Suh, Young Ho; Lee, Min Jae
2017-01Covalent Guanosine Mimetic Inhibitors of G12C KRASXiong, Yuan; Lu, Jia; Hunter, John; Li, Lianbo; Scott, David; Choi, Hwan Geun; Lim, Sang Min; Manandhar, Anuj; Gondi, Sudershan; Sim, Taebo; Westover, Kenneth D.; Gray, Nathanael S.
2020-01-21Decoding Principles of Selective GPCR-G alpha CouplingLim, Sang Min
2017-10Discovery of non-peptidic small molecule inhibitors of cyclophilin D as neuroprotective agents in A beta-induced mitochondrial dysfunctionPark, Insun; Londhe, Ashwini M.; Lim, Ji Woong; Park, Beoung-Geon; Jung, Seo Yun; Lee, Jae Yeol; Lim, Sang Min; No, Kyoung Tai; Lee, Jiyoun; Pae, Ae Nim
2017-12-01Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against A beta-induced neurotoxicityKim, TaeHun; Son, Woo Seung; Morshed, Mohammad Neaz; Londhe, Ashwini M.; Jung, Seo Yun; Park, Jong-Hyun; Park, Woo-Kyu; Lim, Sang Min; Park, Ki Duk; Cho, Sung Jin; Jeong, Kyu-Sung; Lee, Jiyoun; Pae, Ae Nim
2020-02-15Evaluation of anti-depressant effects of phthalazinone-based triple-acting small molecules against 5-HT2A, 5-HT2C, and the serotonin transporterKim, Jihye; Cha, Eunji; Park, Woo Kyu; Lee, Hye Yeon; Lim, Sang Min; Kim, Hak Joong; Pae, Ae Nim
2023-08Exploration of Tetrahydroisoquinoline- and Benzo[c]azepine-Based Sphingosine 1-Phosphate Receptor 1 Agonists for the Treatment of Multiple SclerosisCha, Eunji; Kim, Jushin; Gotina, Lizaveta; Kim, Jaehwan; Kim, Hyeon Jeong; Seo, Seon Hee; Park, Jeong-Eun; Joo, Jeongmin; Kang, Minsik; Lee, Jaeick; Hwang, Hayoung; Kim, Hak Joong; Pae, Ae Nim; Park, Ki Duk; Park, Jong-Hyun; Lim, Sang Min
2018-08GRP78-targeted in-silico virtual screening of novel anticancer agentsViswanath, Ambily Nath Indu; Lim, Ji Woong; Seo, Seon Hee; Lee, Jae Yeol; Lim, Sang Min; Pae, Ae Nim
2018-09-05Identification of crizotinib derivatives as potent SHIP2 inhibitors for the treatment of Alzheimer's diseaseLim, Ji Woong; Kim, Seok Kyu; Choi, Seo Yun; Kim, Dong Hoi; Gadhe, Changdev G.; Lee, Hae Nim; Kim, Hyo-Ji; Kim, Jina; Cho, Sung Jin; Hwang, Hayoung; Seong, Jihye; Jeong, Kyu-Sung; Lee, Jae Yeol; Lim, Sang Min; Lee, Jae Wook; Pae, Ae Nim
2016-12Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependentlyViswanath, Ambily Nath Indu; Jung, Seo Yun; Hwang, Eun Mi; Park, Ki Duk; Lim, Sang Min; Min, Sun-Joon; Cho, Yong Seo; Pae, Ae Nim
2017-12In silico-designed novel non-peptidic ABAD L-D hot spot mimetics reverse A-induced mitochondrial impairments in vitroViswanath, Ambily Nath Indu; Kim, TaeHun; Jung, Seo Yun; Lim, Sang Min; Pae, Ae Nim
2024-01Insights to develop tau-directed therapeutics to protect the synaptic integrity for tauopathiesCha, Eunji; Kim, Hak Joong; Lim, Sang Min
2020-01Introducing "Future of Biochemistry 2020: The Asia-Pacific Issue"Ananthanarayanan, Vaishnavi; Chattopadhyay, Kausik; Chen, Lei; Cheng, Liang; Edgington-Mitchell, Laura; Eswarappa, Sandeep; Hussain, Tanweer; Kambe, Taiho; Kim, Seokhee; Lee, Jun-Seok; Lee, Mihye; Li, Xuechen; Lim, Mi Hee; Lim, Sang Min; Lin, Shixian; Liu, Tao; Mahalakshmi, Radhakrishnan; Maji, Samir K.; Naganathan, Athi N.; Nomura, Wataru; Passioura, Toby; Rao, Yu; Reddy, Govardhan; Rhee, Hyun-Woo; Sekhar, Ashok; Seo, Jiwon; Shukla, Arun Kumar; Singh, Mahavir; Song, Woon Ju; Sun, Hongyan; Tamura, Tomonori; Tang, Chun; Tsukiji, Shinya; Yang, Cai-Guang; Yi, Chengqi; Zou, Peng; Schepartz, Alanna
2019-11Investigation of Molecular Details of Keap1-Nrf2 Inhibitors Using Molecular Dynamics and Umbrella Sampling TechniquesLondhe, Ashwini Machhindra; Gadhe, Changdev Gorakshnath; Lim, Sang Min; Pae, Ae Nim
2017-12-18Ligand-controlled Regiodivergent C-H Alkenylation of Pyrazoles and its Application to the Synthesis of IndazolesKim, Hyun Tae; Ha, Hyeri; Kang, Geunhee; Kim, Og Soon; Ryu, Ho; Biswas, Abul Kalam; Lim, Sang Min; Baik, Mu-Hyun; Joo, Jung Min
2020-01Metabolic engineering of Escherichia coli to produce a monophosphoryl lipid A adjuvantJi, Yuhyun; An, Jinsu; Hwang, Dohyeon; Ha, Da Hui; Lim, Sang Min; Lee, Chankyu; Zhao, Jinshi; Song, Hyun Kyu; Yang, Eun Gyeong; Zhou, Pei; Chung, Hak Suk
2020-05Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal modelKim, Siwon; Viswanath, Ambily Nath Indu; Park, Jong-Hyun; Lee, Ha Eun; Park, A. Yeong; Choi, Ji Won; Kim, Hyeon Jeong; Londhe, Ashwini M.; Jang, Bo Ko; Lee, Jaeick; Hwang, Hayoung; Lim, Sang Min; Pae, Ae Nim; Park, Ki Duk
2016-11-10Optimization and biological evaluation of aminopyrimidine-based I kappa B kinase beta inhibitors with potent anti-inflammatory effectsShin, Yongje; Lim, Sang Min; Yan, Hong Hua; Jung, Sungwoo; Fang, Zhenghuan; Jung, Kyung Hee; Hong, Soon-Sun; Hong, Sungwoo
2014-12Pharmacological targeting of the pseudokinase Her3Xie, Ting; Lim, Sang Min; Westover, Kenneth D.; Dodge, Michael E.; Ercan, Dalia; Ficarro, Scott B.; Udayakumar, Durga; Gurbani, Deepak; Tae, Hyun Seop; Riddle, Steven M.; Sim, Taebo; Marto, Jarrod A.; Jaenne, Pasi A.; Crews, Craig M.; Gray, Nathanael S.
2021-06Pharmacophore-Based Virtual Screening of Novel Competitive Inhibitors of the Neurodegenerative Disease Target Kynurenine-3-MonooxygenaseGotina, Lizaveta; Seo, Seon Hee; Kim, Chae Won; Lim, Sang Min; Pae, Ae Nim
2017-03-28Small molecule selectively suppresses MYC transcription in cancer cellsBouvard, Claire; Lim, Sang Min; Ludka, John; Yazdani, Nahid; Woods, Ashley K.; Chatterjee, Arnab K.; Schultz, Peter G.; Zhu, Shoutian
2022-09Structural hybridization for inhibitors of the interaction between NRF2 and Keap1Lee, Dong Heun; Seo, Seon Hee; Gotina, Lizaveta; Pae, Ae Nim; Lim, Sang Min
2019-05-15Structural hybridization of pyrrolidine-based T-type calcium channel inhibitors and exploration of their analgesic effects in a neuropathic pain modelSon, Woo Seung; Jeong, Kyu-Sung; Lim, Sang Min; Pae, Ae Nim
2018-09-20Synthesis and biological evaluation of pyrrolidine-based T-type calcium channel inhibitors for the treatment of neuropathic painYang, Hak Kyun; Son, Woo Seung; Lim, Keon Seung; Kim, Gun Hee; Lim, Eun Jeong; Gadhe, Changdev G.; Lee, Jae Yeol; Jeong, Kyu-Sung; Lim, Sang Min; Pae, Ae Nim
2014-01-03Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site InhibitorLim, Sang Min; Westover, Kenneth D.; Ficarro, Scott B.; Harrison, Rane A.; Choi, Hwan Geun; Pacold, Michael E.; Carrasco, Martin; Hunter, John; Kim, Nam Doo; Xie, Ting; Sim, Taebo; Jaenne, Pasi A.; Meyerson, Matthew; Marto, Jarrod A.; Engen, John R.; Gray, Nathanael S.
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