DSpace at KISTKIST Article2020

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dc.contributor.authorKim, Taehyung-
dc.contributor.authorHyun, Hana-
dc.contributor.authorHeo, Roun-
dc.contributor.authorNam, Keonwook-
dc.contributor.authorYang, Kyungjik-
dc.contributor.authorKim, Young Min-
dc.contributor.authorLee, Yoon Suk-
dc.contributor.authorAn, Jae Yoon-
dc.contributor.authorPark, Jae Hyung-
dc.contributor.authorChoi, Ki Young-
dc.contributor.authorRoh, Young Hoon-
dc.date.accessioned2024-01-19T17:30:36Z-
dc.date.available2024-01-19T17:30:36Z-
dc.date.created2021-09-05-
dc.date.issued2020-06-21-
dc.identifier.issn1359-7345-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/118513-
dc.description.abstractA new dual-targeting polymeric siRNA nanoparticle (Dual-PSNP) was developed via multiple processes: rolling circle transcription, condensation, electrostatic deposition, and click chemistry. The Dual-PSNP showed significantly improved cancer-specific intracellular delivery, gene knockdown efficacy, and apoptosis-mediated cytotoxicity through additive receptor-mediated interactions of the two ligands.-
dc.languageEnglish-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectPROGRESS REPORT-
dc.subjectIN-VITRO-
dc.subjectMICROSPONGES-
dc.subjectINTERFERENCE-
dc.subjectNANOCARRIERS-
dc.subjectCHALLENGES-
dc.subjectDISEASE-
dc.titleDual-targeting RNA nanoparticles for efficient delivery of polymeric siRNA to cancer cells-
dc.typeArticle-
dc.identifier.doi10.1039/d0cc01848a-
dc.description.journalClass1-
dc.identifier.bibliographicCitationCHEMICAL COMMUNICATIONS, v.56, no.49, pp.6624 - 6627-
dc.citation.titleCHEMICAL COMMUNICATIONS-
dc.citation.volume56-
dc.citation.number49-
dc.citation.startPage6624-
dc.citation.endPage6627-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000543208800029-
dc.identifier.scopusid2-s2.0-85086747115-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusPROGRESS REPORT-
dc.subject.keywordPlusIN-VITRO-
dc.subject.keywordPlusMICROSPONGES-
dc.subject.keywordPlusINTERFERENCE-
dc.subject.keywordPlusNANOCARRIERS-
dc.subject.keywordPlusCHALLENGES-
dc.subject.keywordPlusDISEASE-
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