DSpace at KISTKIST Article2018

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dc.contributor.authorHien Bao Dieu Thai-
dc.contributor.authorLevi-Acobas, Fabienne-
dc.contributor.authorYum, Soo-Young-
dc.contributor.authorJang, Goo-
dc.contributor.authorHollenstein, Marcel-
dc.contributor.authorAhn, Dae-Ro-
dc.date.accessioned2024-01-19T22:00:49Z-
dc.date.available2024-01-19T22:00:49Z-
dc.date.created2022-01-10-
dc.date.issued2018-09-04-
dc.identifier.issn1359-7345-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/120931-
dc.description.abstractWe prepared tetrahedral DNAzymes (TDzs) to overcome potential limitations such as insufficient serum stability and poor cellular uptake of single-stranded DNAzymes (ssDzs). TDzs showed enhanced serum stability and higher cellular uptake efficiency compared to those of ssDzs, providing significantly improved intracellular gene-silencing activity to down-regulate the target mRNA level.-
dc.languageEnglish-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectIN-VITRO SELECTION-
dc.subjectDNA NANOSTRUCTURES-
dc.subjectANTISENSE OLIGONUCLEOTIDES-
dc.subjectDELIVERY-
dc.subjectRNA-
dc.subjectDEOXYRIBOZYMES-
dc.subjectNANOCARRIERS-
dc.subjectTOLERABILITY-
dc.subjectSTABILITY-
dc.subjectENZYMES-
dc.titleTetrahedral DNAzymes for enhanced intracellular gene-silencing activity-
dc.typeArticle-
dc.identifier.doi10.1039/c8cc05721d-
dc.description.journalClass1-
dc.identifier.bibliographicCitationCHEMICAL COMMUNICATIONS, v.54, no.68, pp.9410 - 9413-
dc.citation.titleCHEMICAL COMMUNICATIONS-
dc.citation.volume54-
dc.citation.number68-
dc.citation.startPage9410-
dc.citation.endPage9413-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000442385200006-
dc.identifier.scopusid2-s2.0-85051942029-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusIN-VITRO SELECTION-
dc.subject.keywordPlusDNA NANOSTRUCTURES-
dc.subject.keywordPlusANTISENSE OLIGONUCLEOTIDES-
dc.subject.keywordPlusDELIVERY-
dc.subject.keywordPlusRNA-
dc.subject.keywordPlusDEOXYRIBOZYMES-
dc.subject.keywordPlusNANOCARRIERS-
dc.subject.keywordPlusTOLERABILITY-
dc.subject.keywordPlusSTABILITY-
dc.subject.keywordPlusENZYMES-
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