Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Baek, H. | - |
dc.contributor.author | Pahk, K.J. | - |
dc.contributor.author | Kim, H. | - |
dc.date.accessioned | 2024-01-20T02:33:11Z | - |
dc.date.available | 2024-01-20T02:33:11Z | - |
dc.date.created | 2021-08-31 | - |
dc.date.issued | 2017-01 | - |
dc.identifier.issn | 2093-9868 | - |
dc.identifier.uri | https://pubs.kist.re.kr/handle/201004/123293 | - |
dc.description.abstract | The ability of ultrasound to be focused into a small region of interest through the intact skull within the brain has led researchers to investigate its potential therapeutic uses for functional neurosurgery and tumor ablation. Studies have used high-intensity focused ultrasound to ablate tissue in localised brain regions for movement disorders and chronic pain while sparing the overlying and surrounding tissue. More recently, low-intensity focused ultrasound (LIFU) that induces reversible biological effects has been emerged as an alternative neuromodulation modality due to its bi-modal (i.e. excitation and suppression) capability with exquisite spatial specificity and depth penetration. Many compelling evidences of LIFU-mediated neuromodulatory effects including behavioral responses, electrophysiological recordings and functional imaging data have been found in the last decades. LIFU, therefore, has the enormous potential to improve the clinical outcomes as well as to replace the currently available neuromodulation techniques such as deep brain stimulation (DBS), transcranial magnetic stimulation and transcranial current stimulation. In this paper, we aim to provide a summary of pioneering studies in the field of ultrasonic neuromodulation including its underlying mechanisms that were published in the last 60?years. In closing, some of potential clinical applications of ultrasonic brain stimulation will be discussed. ? 2017, Korean Society of Medical and Biological Engineering and Springer. | - |
dc.language | English | - |
dc.publisher | Springer Verlag | - |
dc.subject | Brain | - |
dc.subject | Electrophysiology | - |
dc.subject | Functional electric stimulation | - |
dc.subject | Surgery | - |
dc.subject | Tissue | - |
dc.subject | Ultrasonics | - |
dc.subject | Electrophysiological recordings | - |
dc.subject | Focused ultrasound | - |
dc.subject | Functional neurosurgery | - |
dc.subject | High intensity focused ultrasound | - |
dc.subject | Low intensity focused ultrasounds | - |
dc.subject | Neuromodulation | - |
dc.subject | Non-invasive | - |
dc.subject | Transcranial magnetic stimulation | - |
dc.subject | Neurosurgery | - |
dc.subject | action potential | - |
dc.subject | blood brain barrier | - |
dc.subject | BOLD signal | - |
dc.subject | brain depth stimulation | - |
dc.subject | chronic pain | - |
dc.subject | depression | - |
dc.subject | echoencephalography | - |
dc.subject | electrocorticography | - |
dc.subject | electroencephalography | - |
dc.subject | electromyography | - |
dc.subject | electrophysiological procedures | - |
dc.subject | functional magnetic resonance imaging | - |
dc.subject | human | - |
dc.subject | low intensity focused ultrasound | - |
dc.subject | neuromodulation | - |
dc.subject | nonhuman | - |
dc.subject | peripheral nervous system function | - |
dc.subject | positron emission tomography | - |
dc.subject | primary somatosensory cortex | - |
dc.subject | priority journal | - |
dc.subject | Review | - |
dc.subject | sensorimotor function | - |
dc.subject | skin sensation | - |
dc.subject | sound intensity | - |
dc.subject | transcranial magnetic stimulation | - |
dc.subject | tumor ablation | - |
dc.subject | ultrasound therapy | - |
dc.title | A review of low-intensity focused ultrasound for neuromodulation | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s13534-016-0007-y | - |
dc.description.journalClass | 1 | - |
dc.identifier.bibliographicCitation | Biomedical Engineering Letters, v.7, no.2, pp.135 - 142 | - |
dc.citation.title | Biomedical Engineering Letters | - |
dc.citation.volume | 7 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 135 | - |
dc.citation.endPage | 142 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.identifier.kciid | ART002245603 | - |
dc.identifier.scopusid | 2-s2.0-85021288426 | - |
dc.type.docType | Review | - |
dc.subject.keywordPlus | Brain | - |
dc.subject.keywordPlus | Electrophysiology | - |
dc.subject.keywordPlus | Functional electric stimulation | - |
dc.subject.keywordPlus | Surgery | - |
dc.subject.keywordPlus | Tissue | - |
dc.subject.keywordPlus | Ultrasonics | - |
dc.subject.keywordPlus | Electrophysiological recordings | - |
dc.subject.keywordPlus | Focused ultrasound | - |
dc.subject.keywordPlus | Functional neurosurgery | - |
dc.subject.keywordPlus | High intensity focused ultrasound | - |
dc.subject.keywordPlus | Low intensity focused ultrasounds | - |
dc.subject.keywordPlus | Neuromodulation | - |
dc.subject.keywordPlus | Non-invasive | - |
dc.subject.keywordPlus | Transcranial magnetic stimulation | - |
dc.subject.keywordPlus | Neurosurgery | - |
dc.subject.keywordPlus | action potential | - |
dc.subject.keywordPlus | blood brain barrier | - |
dc.subject.keywordPlus | BOLD signal | - |
dc.subject.keywordPlus | brain depth stimulation | - |
dc.subject.keywordPlus | chronic pain | - |
dc.subject.keywordPlus | depression | - |
dc.subject.keywordPlus | echoencephalography | - |
dc.subject.keywordPlus | electrocorticography | - |
dc.subject.keywordPlus | electroencephalography | - |
dc.subject.keywordPlus | electromyography | - |
dc.subject.keywordPlus | electrophysiological procedures | - |
dc.subject.keywordPlus | functional magnetic resonance imaging | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | low intensity focused ultrasound | - |
dc.subject.keywordPlus | neuromodulation | - |
dc.subject.keywordPlus | nonhuman | - |
dc.subject.keywordPlus | peripheral nervous system function | - |
dc.subject.keywordPlus | positron emission tomography | - |
dc.subject.keywordPlus | primary somatosensory cortex | - |
dc.subject.keywordPlus | priority journal | - |
dc.subject.keywordPlus | Review | - |
dc.subject.keywordPlus | sensorimotor function | - |
dc.subject.keywordPlus | skin sensation | - |
dc.subject.keywordPlus | sound intensity | - |
dc.subject.keywordPlus | transcranial magnetic stimulation | - |
dc.subject.keywordPlus | tumor ablation | - |
dc.subject.keywordPlus | ultrasound therapy | - |
dc.subject.keywordAuthor | Brain | - |
dc.subject.keywordAuthor | Focused ultrasound | - |
dc.subject.keywordAuthor | Neuromodulation | - |
dc.subject.keywordAuthor | Non-invasive | - |
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