DSpace at KISTKIST Article2015

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dc.contributor.authorLee, Wonhwa-
dc.contributor.authorSeo, Junyoung-
dc.contributor.authorKwak, Soyoung-
dc.contributor.authorPark, Eun Ji-
dc.contributor.authorNa, Dong Hee-
dc.contributor.authorKim, Soyoun-
dc.contributor.authorLee, You Mie-
dc.contributor.authorKim, In-San-
dc.contributor.authorBae, Jong-Sup-
dc.date.accessioned2024-01-20T05:33:32Z-
dc.date.available2024-01-20T05:33:32Z-
dc.date.created2021-09-03-
dc.date.issued2015-11-11-
dc.identifier.issn0935-9648-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/124756-
dc.description.abstractNew protein nanocages are designed bearing two functional proteins, gamma-carboxyglutamic acid of protein C (PC-Gla) and thrombin receptor agonist peptide (TRAP), and have an anti-septic response. These nanoparticles reduce sepsis-induced organ injury and septic mortality in vivo. Noting that there are currently no medications for severe sepsis, these results show that novel nanoparticles can be used to treat sepsis.-
dc.languageEnglish-
dc.publisherWILEY-V C H VERLAG GMBH-
dc.subjectENDOTHELIAL-CELLS-
dc.subjectADHESION MOLECULES-
dc.subjectSERUM FERRITIN-
dc.subjectNANOPARTICLES-
dc.subjectACTIVATION-
dc.subjectEXPRESSION-
dc.subjectPATHWAY-
dc.subjectANTICOAGULANT-
dc.subjectEPIDEMIOLOGY-
dc.subjectPERMEABILITY-
dc.titleA Double-Chambered Protein Nanocage Loaded with Thrombin Receptor Agonist Peptide (TRAP) and gamma-Carboxyglutamic Acid of Protein C (PC-Gla) for Sepsis Treatment-
dc.typeArticle-
dc.identifier.doi10.1002/adma.201503093-
dc.description.journalClass1-
dc.identifier.bibliographicCitationADVANCED MATERIALS, v.27, no.42, pp.6637 - +-
dc.citation.titleADVANCED MATERIALS-
dc.citation.volume27-
dc.citation.number42-
dc.citation.startPage6637-
dc.citation.endPage+-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000364700200011-
dc.identifier.scopusid2-s2.0-84946763409-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalWebOfScienceCategoryChemistry, Physical-
dc.relation.journalWebOfScienceCategoryNanoscience & Nanotechnology-
dc.relation.journalWebOfScienceCategoryMaterials Science, Multidisciplinary-
dc.relation.journalWebOfScienceCategoryPhysics, Applied-
dc.relation.journalWebOfScienceCategoryPhysics, Condensed Matter-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalResearchAreaScience & Technology - Other Topics-
dc.relation.journalResearchAreaMaterials Science-
dc.relation.journalResearchAreaPhysics-
dc.type.docTypeArticle-
dc.subject.keywordPlusENDOTHELIAL-CELLS-
dc.subject.keywordPlusADHESION MOLECULES-
dc.subject.keywordPlusSERUM FERRITIN-
dc.subject.keywordPlusNANOPARTICLES-
dc.subject.keywordPlusACTIVATION-
dc.subject.keywordPlusEXPRESSION-
dc.subject.keywordPlusPATHWAY-
dc.subject.keywordPlusANTICOAGULANT-
dc.subject.keywordPlusEPIDEMIOLOGY-
dc.subject.keywordPlusPERMEABILITY-
dc.subject.keywordAuthorferritin-
dc.subject.keywordAuthornanoparticles-
dc.subject.keywordAuthorPC-gla-
dc.subject.keywordAuthorsepsis-
dc.subject.keywordAuthorTRAP-
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