Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Shin, Seunghoon | - |
dc.contributor.author | Gihm, Se Hoon | - |
dc.contributor.author | Park, Chong Rae | - |
dc.contributor.author | Kim, Sehoon | - |
dc.contributor.author | Park, Soo Young | - |
dc.date.accessioned | 2024-01-20T11:34:30Z | - |
dc.date.available | 2024-01-20T11:34:30Z | - |
dc.date.created | 2021-09-05 | - |
dc.date.issued | 2013-08-27 | - |
dc.identifier.issn | 0897-4756 | - |
dc.identifier.uri | https://pubs.kist.re.kr/handle/201004/127754 | - |
dc.description.abstract | We report synthesis and optical/structural characterization of new fluorescent rod-coil amphiphiles based on the PEGylated alpha-cyanostilbene skeleton (12EO-CNMBE and 12EO-CNTFMBE) and their self-assembly behaviors in water. Distinct from the common amphiphilic behavior of nonfluorinated 12EO-CNMBE forming spherical nanostructures, fluorinated 12EO-CNTFMBE has proven to be the first example of a molecular building block that can self-assemble in water into small-dimension, small-aspect-ratio organic nanorods with aggregation-induced enhanced emission (AIEE). The robust structural integrity and hydrophobic/pi-conjugated nature of the fluorinated block assembly, as well as the antifouling coating by the hydrophilic PEG block, enabled stable encapsulation of a model drug (Nile Red) within the self-assembled nanorod structure and its successful delivery through membrane filters. By virtue of these advantageous attributes along with high intracellular uptake efficiency, the 12EO-CNTFMBE nanorods manifested potential as a seff-signaling fluorescent nanocarrier for the intracellular delivery of hydrophobic cargos. | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.subject | DRUG-DELIVERY | - |
dc.subject | SPECTROSCOPY | - |
dc.title | Water-Soluble Fluorinated and PEGylated Cyanostilbene Derivative: An Amphiphilic Building Block Forming Self-Assembled Organic Nanorods with Enhanced Fluorescence Emission | - |
dc.type | Article | - |
dc.identifier.doi | 10.1021/cm400988a | - |
dc.description.journalClass | 1 | - |
dc.identifier.bibliographicCitation | CHEMISTRY OF MATERIALS, v.25, no.16, pp.3288 - 3295 | - |
dc.citation.title | CHEMISTRY OF MATERIALS | - |
dc.citation.volume | 25 | - |
dc.citation.number | 16 | - |
dc.citation.startPage | 3288 | - |
dc.citation.endPage | 3295 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.identifier.wosid | 000323810800002 | - |
dc.identifier.scopusid | 2-s2.0-84883242747 | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | DRUG-DELIVERY | - |
dc.subject.keywordPlus | SPECTROSCOPY | - |
dc.subject.keywordAuthor | aggregation-induced enhanced emission | - |
dc.subject.keywordAuthor | bioimaging | - |
dc.subject.keywordAuthor | cellular delivery carrier | - |
dc.subject.keywordAuthor | fluorinated/PEGylated amphiphile | - |
dc.subject.keywordAuthor | organic nanorods | - |
dc.subject.keywordAuthor | self-assembly | - |
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