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dc.contributor.authorShin, Seunghoon-
dc.contributor.authorGihm, Se Hoon-
dc.contributor.authorPark, Chong Rae-
dc.contributor.authorKim, Sehoon-
dc.contributor.authorPark, Soo Young-
dc.date.accessioned2024-01-20T11:34:30Z-
dc.date.available2024-01-20T11:34:30Z-
dc.date.created2021-09-05-
dc.date.issued2013-08-27-
dc.identifier.issn0897-4756-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/127754-
dc.description.abstractWe report synthesis and optical/structural characterization of new fluorescent rod-coil amphiphiles based on the PEGylated alpha-cyanostilbene skeleton (12EO-CNMBE and 12EO-CNTFMBE) and their self-assembly behaviors in water. Distinct from the common amphiphilic behavior of nonfluorinated 12EO-CNMBE forming spherical nanostructures, fluorinated 12EO-CNTFMBE has proven to be the first example of a molecular building block that can self-assemble in water into small-dimension, small-aspect-ratio organic nanorods with aggregation-induced enhanced emission (AIEE). The robust structural integrity and hydrophobic/pi-conjugated nature of the fluorinated block assembly, as well as the antifouling coating by the hydrophilic PEG block, enabled stable encapsulation of a model drug (Nile Red) within the self-assembled nanorod structure and its successful delivery through membrane filters. By virtue of these advantageous attributes along with high intracellular uptake efficiency, the 12EO-CNTFMBE nanorods manifested potential as a seff-signaling fluorescent nanocarrier for the intracellular delivery of hydrophobic cargos.-
dc.languageEnglish-
dc.publisherAMER CHEMICAL SOC-
dc.subjectDRUG-DELIVERY-
dc.subjectSPECTROSCOPY-
dc.titleWater-Soluble Fluorinated and PEGylated Cyanostilbene Derivative: An Amphiphilic Building Block Forming Self-Assembled Organic Nanorods with Enhanced Fluorescence Emission-
dc.typeArticle-
dc.identifier.doi10.1021/cm400988a-
dc.description.journalClass1-
dc.identifier.bibliographicCitationCHEMISTRY OF MATERIALS, v.25, no.16, pp.3288 - 3295-
dc.citation.titleCHEMISTRY OF MATERIALS-
dc.citation.volume25-
dc.citation.number16-
dc.citation.startPage3288-
dc.citation.endPage3295-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000323810800002-
dc.identifier.scopusid2-s2.0-84883242747-
dc.relation.journalWebOfScienceCategoryChemistry, Physical-
dc.relation.journalWebOfScienceCategoryMaterials Science, Multidisciplinary-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalResearchAreaMaterials Science-
dc.type.docTypeArticle-
dc.subject.keywordPlusDRUG-DELIVERY-
dc.subject.keywordPlusSPECTROSCOPY-
dc.subject.keywordAuthoraggregation-induced enhanced emission-
dc.subject.keywordAuthorbioimaging-
dc.subject.keywordAuthorcellular delivery carrier-
dc.subject.keywordAuthorfluorinated/PEGylated amphiphile-
dc.subject.keywordAuthororganic nanorods-
dc.subject.keywordAuthorself-assembly-
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KIST Article > 2013
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