Improvement of mechanical properties and blood compatibility of PLLA nanocomposites by incorporation of polyhedral oligomeric silsesquioxane

Authors
Bach, Quang VuChoi, JiyeonJoung, Yoon KiPark, Bang JuHan, Dong Keun
Issue Date
2012-09
Publisher
POLYMER SOC KOREA
Citation
MACROMOLECULAR RESEARCH, v.20, no.9, pp.996 - 1001
Abstract
A series of hybrid nanocomposites containing poly(L-lactide) (PLLA) and polyhedral oligomeric silsesquioxane (POSS) was prepared by solvent casting method for the enhancement of the mechanical properties of PLLA. One of them was mixed by only a physical blending between PLLA and POSS to form PLLA/POSS nanocomposite that did not show considerable improvement. In the other hand, two types of PLLA-POSS additives were synthesized via the ring-opening polymerization of L-lactide in the presence of POSS in different content. On these additives, POSS played as not only an initiator for the ring-opening polymerization reaction due to its hydroxyl functional groups on the surface but also a type of hybrid filler for PLLA/PLLA-POSS nanocomposite after mixing with PLLA matrix. PLLA/PLLA-POSS composite showed significant improvement in mechanical properties because of covalent bonding between PLLA and POSS. In particular, the tensile modulus has been apparently increased in PLLA/5PLLA-5POSS nanocomposites (1,449 MPa) with respect to PLLA control (498 MPa). SEM and XRD data indicated that the dispersion of PLLA-modified POSS was better than that of POSS in PLLA matrix. Although the contact angle was not significantly different, the protein adsorption and platelet adhesion are reduced slightly in PLLA/PLLA-POSS nanocomposite as compared to those of PLLA control and PLLA/POSS. Therefore, it is expected that biodegradable POSS nanocomposite may be helpful to be utilized in biomedical devices such as drug-eluting stents and artificial implants.
Keywords
THERMAL-PROPERTIES; POSS; BIOCOMPATIBILITY; BIODEGRADATION; COPOLYMERS; POLYMERS; THERMAL-PROPERTIES; POSS; BIOCOMPATIBILITY; BIODEGRADATION; COPOLYMERS; POLYMERS; PLLA; POSS; nanocomposite; mechanical property; blood compatibility
ISSN
1598-5032
URI
https://pubs.kist.re.kr/handle/201004/128948
DOI
10.1007/s13233-012-0196-x
Appears in Collections:
KIST Article > 2012
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