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Aldose Reductase Inhibitory Activity of the Compounds from the Seed of Psoralea corylifolia

Authors: Shim, Sang Hee; Kim, Yujin; Lee, Joo Young; Song, Dae-Geun; Pan, Cheol-Ho; Jung, Sang Hoon

Issue Date: 2009-10

Publisher: KOREAN SOC APPLIED BIOLOGICAL CHEMISTRY

Citation: JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, v.52, no.5, pp.568 - 572

Abstract: The purpose of this study was to evaluate the active properties of Psoralea corylifolia seed for the treatment of diabetic complications. 6-Prenylnaringenin (5) and corylin (6) isolated from P. corylifolia could possibly be acting as the active compounds for the inhibition of aldose reductase and would be the lead compounds for the aldose reductase inhibitors.

Keywords: STRUCTURAL REQUIREMENTS; DIABETIC COMPLICATIONS; FLAVONOIDS; SORBINIL; FINGERPRINT; RETINOPATHY; PREVENTION; GLYCATION; BAKUCHIOL; TRIAL; STRUCTURAL REQUIREMENTS; DIABETIC COMPLICATIONS; FLAVONOIDS; SORBINIL; FINGERPRINT; RETINOPATHY; PREVENTION; GLYCATION; BAKUCHIOL; TRIAL; aldose reductase; corylin; 6-prenylnaringenin; Psoralea corylifolia

ISSN: 1738-2203

URI: https://pubs.kist.re.kr/handle/201004/132099

DOI: 10.3839/jksabc.2009.096

Appears in Collections:: KIST Article > 2009

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