DSpace at KISTKIST Article2006

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dc.contributor.authorJeon, H. C.-
dc.contributor.authorKim, J. -W.-
dc.contributor.authorHong, J. H.-
dc.contributor.authorCho, J. -H.-
dc.contributor.authorOh, C. -H.-
dc.date.accessioned2024-01-21T02:30:25Z-
dc.date.available2024-01-21T02:30:25Z-
dc.date.created2021-08-31-
dc.date.issued2006-10-
dc.identifier.issn0223-5234-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/135093-
dc.description.abstractThe synthesis of a new series of 1 beta-methylcarbapenems having pyrrolidine and piperidine moieties is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bacteria were tested and the effect of substituent on the pyrrolidine ring was investigated. A particular compound (IIIb) having hydroxypyrrolidine moiety showed the most potent antibacterial activity. (c) 2006 Elsevier Masson SAS. All rights reserved.-
dc.languageEnglish-
dc.publisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER-
dc.subjectBETA-LACTAM ANTIBIOTICS-
dc.subjectANTIBACTERIAL ACTIVITY-
dc.subjectCARBAPENEM ANTIBIOTICS-
dc.subjectTHIENAMYCIN-
dc.titleSynthesis and in vitro activity of a series 1 beta-methylcarbapenem derivatives-
dc.typeArticle-
dc.identifier.doi10.1016/j.ejmech.2006.05.003-
dc.description.journalClass1-
dc.identifier.bibliographicCitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.41, no.10, pp.1201 - 1209-
dc.citation.titleEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY-
dc.citation.volume41-
dc.citation.number10-
dc.citation.startPage1201-
dc.citation.endPage1209-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000241909800010-
dc.identifier.scopusid2-s2.0-33749627044-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.type.docTypeArticle-
dc.subject.keywordPlusBETA-LACTAM ANTIBIOTICS-
dc.subject.keywordPlusANTIBACTERIAL ACTIVITY-
dc.subject.keywordPlusCARBAPENEM ANTIBIOTICS-
dc.subject.keywordPlusTHIENAMYCIN-
dc.subject.keywordAuthor1 beta-methylcarbapenems-
dc.subject.keywordAuthorantibacterial activity-
dc.subject.keywordAuthorsubstituent effects-
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