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dc.contributor.authorKim, Jin-Woong-
dc.contributor.authorPark, Hyeong Beom-
dc.contributor.authorChung, Bong Young-
dc.contributor.authorLee, Jong Baek-
dc.contributor.authorCho, Jung-Hyuck-
dc.contributor.authorOh, Chang-Hyun-
dc.date.accessioned2024-01-21T02:33:56Z-
dc.date.available2024-01-21T02:33:56Z-
dc.date.created2021-09-01-
dc.date.issued2006-08-20-
dc.identifier.issn0253-2964-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/135238-
dc.description.abstractThe synthesis of a new series of 1 beta-methylcarbapenems having 5-(alpha,beta-disubstituted ethyl)pyrrolidine moiety is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bacteria were tested and the effect of substituents on the pyrrolidine ring was investigated. A particular compound (VIh) having alpha-hydroxy-beta-piperazinylethyl substituted moiety showed the most potent activity.-
dc.languageEnglish-
dc.publisherWILEY-V C H VERLAG GMBH-
dc.subjectBETA-LACTAM ANTIBIOTICS-
dc.subjectCARBAPENEM ANTIBIOTICS-
dc.subjectTHIENAMYCIN-
dc.subject1-BETA-METHYLCARBAPENEM-
dc.titleSynthesis and antibacterial activity of 1 beta-methyl-2-[5-(alpha,beta-disubstituted ethyl)pyrrolidin-3-ylthio]carbapenem derivatives. Part II-
dc.typeArticle-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.27, no.8, pp.1164 - 1170-
dc.citation.titleBULLETIN OF THE KOREAN CHEMICAL SOCIETY-
dc.citation.volume27-
dc.citation.number8-
dc.citation.startPage1164-
dc.citation.endPage1170-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.identifier.kciidART001021933-
dc.identifier.wosid000240394100013-
dc.identifier.scopusid2-s2.0-33747848946-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusBETA-LACTAM ANTIBIOTICS-
dc.subject.keywordPlusCARBAPENEM ANTIBIOTICS-
dc.subject.keywordPlusTHIENAMYCIN-
dc.subject.keywordPlus1-BETA-METHYLCARBAPENEM-
dc.subject.keywordAuthor1 beta-methylcarbapenem-
dc.subject.keywordAuthorantibacterial activity-
dc.subject.keywordAuthorDHP-I stability-
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