DSpace at KISTKIST Article2005

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dc.contributor.authorSaleem, M-
dc.contributor.authorKim, HJ-
dc.contributor.authorAli, MS-
dc.contributor.authorLee, YS-
dc.date.accessioned2024-01-21T04:08:14Z-
dc.date.available2024-01-21T04:08:14Z-
dc.date.created2021-09-04-
dc.date.issued2005-11-
dc.identifier.issn0265-0568-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/136016-
dc.description.abstractLignans are a class of secondary plant metabolites produced by oxidative dimerization of two phenylpropanoid units. Although their molecular backbone consists only of two phenylpropane (C-6-C-3) units, lignans show an enormous structural diversity. There is a growing interest in lignans and their synthetic derivatives due to applications in cancer chemotherapy and various other pharmacological effects. This review deals with lignans possessing anticancer, antioxidant, antimicrobial, anti-inflammatory and immunosuppressive activities, and comprises the data reported in more than 100 peer-reviewed articles, so as to highlight the recently reported bioactive lignans that could be a first step towards the development of potential new therapeutic agents.-
dc.languageEnglish-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectFACTOR-ALPHA PRODUCTION-
dc.subjectNITRIC-OXIDE SYNTHASE-
dc.subjectANTIOXIDANT ACTIVITY-
dc.subjectMACHILUS-THUNBERGII-
dc.subjectSAURURUS-CHINENSIS-
dc.subjectTNF-ALPHA-
dc.subjectIN-VITRO-
dc.subjectDIBENZYLBUTYROLACTONE LIGNANS-
dc.subjectPHOSPHOLIPASE C-GAMMA-1-
dc.subjectCCL4-INDUCED TOXICITY-
dc.titleAn update on bioactive plant lignans-
dc.typeArticle-
dc.identifier.doi10.1039/b514045p-
dc.description.journalClass1-
dc.identifier.bibliographicCitationNATURAL PRODUCT REPORTS, v.22, no.6, pp.696 - 716-
dc.citation.titleNATURAL PRODUCT REPORTS-
dc.citation.volume22-
dc.citation.number6-
dc.citation.startPage696-
dc.citation.endPage716-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000233459100002-
dc.identifier.scopusid2-s2.0-29244452570-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeReview-
dc.subject.keywordPlusFACTOR-ALPHA PRODUCTION-
dc.subject.keywordPlusNITRIC-OXIDE SYNTHASE-
dc.subject.keywordPlusANTIOXIDANT ACTIVITY-
dc.subject.keywordPlusMACHILUS-THUNBERGII-
dc.subject.keywordPlusSAURURUS-CHINENSIS-
dc.subject.keywordPlusTNF-ALPHA-
dc.subject.keywordPlusIN-VITRO-
dc.subject.keywordPlusDIBENZYLBUTYROLACTONE LIGNANS-
dc.subject.keywordPlusPHOSPHOLIPASE C-GAMMA-1-
dc.subject.keywordPlusCCL4-INDUCED TOXICITY-
dc.subject.keywordAuthorbioactive plant-
dc.subject.keywordAuthorlignans-
dc.subject.keywordAuthorAnticancer plant lignans-
dc.subject.keywordAuthorAnti-inflammatory plant lignans-
dc.subject.keywordAuthorAntimicrobial plant lignans-
dc.subject.keywordAuthorAntioxidative plant lignans-
dc.subject.keywordAuthorImmunosuppressive activities of plant lignans-
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