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dc.contributor.authorLee, YS-
dc.contributor.authorLee, YS-
dc.contributor.authorLee, JY-
dc.contributor.authorKim, SN-
dc.contributor.authorLee, CK-
dc.contributor.authorPark, H-
dc.date.accessioned2024-01-21T13:05:05Z-
dc.date.available2024-01-21T13:05:05Z-
dc.date.created2021-09-04-
dc.date.issued2000-12-
dc.identifier.issn0960-894X-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/140838-
dc.description.abstractHIV protease inhibitors containing 6-hydroxy-1,3-dioxin-4-one ring system as a new scaffold have been prepared. Among them, compound 4d showed potent HIV protease inhibitory activity (IC(50) = 0.01 muM) and antiviral activity in cell culture (EC(50) = 0.96 muM, SI = 65.69). (C) 2000 Elsevier Science Ltd. All rights reserved.-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.title6-hydroxy-1,3-dioxin-4-ones as non-peptidic HIV protease inhibitors-
dc.typeArticle-
dc.identifier.doi10.1016/S0960-894X(00)00534-5-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.10, no.23, pp.2625 - 2627-
dc.citation.titleBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.citation.volume10-
dc.citation.number23-
dc.citation.startPage2625-
dc.citation.endPage2627-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000165643300010-
dc.identifier.scopusid2-s2.0-0034606476-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusCOMPETITIVE-INHIBITION-
dc.subject.keywordPlusDESIGN-
dc.subject.keywordAuthorHIV-
dc.subject.keywordAuthornon-peptidic-
dc.subject.keywordAuthorinhibitor-
dc.subject.keywordAuthorpyrone-
dc.subject.keywordAuthor1,3-dioxin-4-one-
dc.subject.keywordAuthorsulfonamide-
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KIST Article > 2000
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