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dc.contributor.author류진-
dc.contributor.author정영미-
dc.contributor.authorChar, Kookheon-
dc.contributor.authorJang, Yeongseon-
dc.date.accessioned2024-01-12T02:33:07Z-
dc.date.available2024-01-12T02:33:07Z-
dc.date.created2022-09-21-
dc.date.issued2023-02-
dc.identifier.issn0167-7799-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/75841-
dc.description.abstractPorous membranes play a critical role in in vitro heterogeneous cell coculture systems because they recapitulate the in vivo microenvironment to mediate physical and biochemical crosstalk between cells. While the conventionally available Transwell® system has been widely used for heterogeneous cell coculture, there are drawbacks to precise control over cell?cell interactions and separation for implantation. The size and numbers of the pores and the thickness of the porous membranes are crucial in determining the efficiency of paracrine signaling and direct junctions between cocultured cells, and significantly impact on the performance of heterogeneous cell cultures. These opportunities and challenges have motivated the design of advanced coculture platforms through improvement of the structural and functional properties of porous membranes. ? 2022 Elsevier Ltd-
dc.languageEnglish-
dc.publisherElsevier BV-
dc.titleAdvances in cell coculture membranes recapitulating in vivo microenvironments-
dc.typeArticle-
dc.identifier.doi10.1016/j.tibtech.2022.07.014-
dc.description.journalClass1-
dc.identifier.bibliographicCitationTrends in Biotechnology, v.41, no.2, pp.214 - 227-
dc.citation.titleTrends in Biotechnology-
dc.citation.volume41-
dc.citation.number2-
dc.citation.startPage214-
dc.citation.endPage227-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000961381300001-
dc.identifier.scopusid2-s2.0-85136589536-
dc.relation.journalWebOfScienceCategoryBiotechnology & Applied Microbiology-
dc.relation.journalResearchAreaBiotechnology & Applied Microbiology-
dc.type.docTypeReview-
dc.subject.keywordPlusCULTURE-
dc.subject.keywordPlusFABRICATION-
dc.subject.keywordPlusSTRATEGIES-
dc.subject.keywordPlusULTRATHIN-
dc.subject.keywordPlusPLATFORM-
dc.subject.keywordPlusSCAFFOLD-
dc.subject.keywordPlusBARRIER-
dc.subject.keywordPlusSYSTEM-
dc.subject.keywordPlusCHIP-
dc.subject.keywordAuthorcell microenvironment-
dc.subject.keywordAuthorcell?cell interaction-
dc.subject.keywordAuthorin vitro coculture-
dc.subject.keywordAuthorporous membrane-
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