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dc.contributor.authorNGUYEN THANH QUA-
dc.contributor.authorKim Jeongyun-
dc.contributor.authorDae woong Lee-
dc.contributor.authorChoi Ji Seob-
dc.contributor.authorPark Jae ho-
dc.contributor.authorJeon, Hojeong-
dc.contributor.author박우태-
dc.contributor.authorLee Sang Youp-
dc.date.accessioned2024-01-12T04:42:52Z-
dc.date.available2024-01-12T04:42:52Z-
dc.date.created2021-09-29-
dc.date.issued2019-07-
dc.identifier.issn2333-2506-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/78510-
dc.description.abstractEmploying magnetic beads (MBs) to microfluidic chips has enabled diverse microscale biomedical applications involving isolation of target molecules, such as, separation, and biosensing. In this report a microfluidic immunoassay chip that can temporarily immobilize MBs for the detection of target biomarkers within a sample solution flown through its channels is introduced. A through-hole structure of the MB capture zone and valves that can control the direction of the flow enabled immobilization of MBs with high reproducibility. Controlling immobilization of MBs shows promise for reproducible immunoassay signal detections for the same concentration of biomarker which is crucial for quantification of the assay. In addition, the structure and position of the captured MBs can potentially be optimal for immunoassay performances where immunoassay reagents including the antigen and the detection antibody are flown through the MB captured through hole maximizing contact for high binding efficiencies.-
dc.languageEnglish-
dc.publisherAMER SOC MECHANICAL ENGINEERS-
dc.titleIMMOBILIZATION OF MAGNETIC BEADS FOR MICROFLUIDIC IMMUNOASSAYS-
dc.typeConference-
dc.description.journalClass1-
dc.identifier.bibliographicCitationASME-JSME-KSME 2019 8th Joint Fluids Engineering Conference-
dc.citation.titleASME-JSME-KSME 2019 8th Joint Fluids Engineering Conference-
dc.citation.conferencePlaceUS-
dc.citation.conferencePlaceSan Francisco, CA-
dc.citation.conferenceDate2019-07-28-
dc.relation.isPartOfPROCEEDINGS OF THE ASME/JSME/KSME JOINT FLUIDS ENGINEERING CONFERENCE, 2019, VOL 4-
dc.identifier.wosid000511529000056-
dc.identifier.scopusid2-s2.0-85076466081-
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KIST Conference Paper > 2019
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