Browsing byAuthorPark, Ki Duk
Showing results 49 to 78 of 89
| Issue Date | Title | Author(s) |
|---|---|---|
| 2021-07 | KDS2010, a Newly Developed Reversible MAO-B Inhibitor, as an Effective Therapeutic Candidate for Parkinson's Disease | Nam, Min-Ho; Park, Jong-Hyun; Song, Hyo jung; Choi, Ji Won; Kim, Siwon; 장보고; Yoon, Hyung Ho; Heo, Jun Young; Lee, Hyowon; An, Heeyoung; Kim, Hyeon Jeong; Park, Sun Jun; Cho, Doo-Wan; Yang, Young-Su; Han, Su-Cheol; Kim, Sangwook; Oh, Soo-Jin; Jeon, Sang Ryong; Park, Ki Duk; Lee, C. Justin |
| 2024-04 | KDS2010, a reversible MAO-B inhibitor, extends the lifetime of neural probes by preventing glial scar formation | Chae, Uikyu; Chun, Heejung; Lim, Jiwoon; Shin, Hyogeun; Smith, Wesley Charles; Choi, Ji Won; Park, Ki Duk; Lee, C. Justin; Cho, Il-Joo |
| 2022-05 | Longitudinal intravital imaging of cerebral microinfarction reveals a dynamic astrocyte reaction leading to glial scar formation | Lee, Jingu; Kim, Joon-Goon; Hong, Sujung; Kim, Young Seo; Ahn, Soyeon; Kim, Ryul; Chun, Heejung; Park, Ki Duk; Jeong, Yong; Kim, Dong-Eog; Lee, C. Justin; Ku, Taeyun; Kim, Pilhan |
| 2019-09 | Mammalian target of rapamycin complex 1 and its downstream effector collapsin response mediator protein-2 drive reinstatement of alcohol reward seeking | Ben Hamida, Sami; Laguesse, Sophie; Morisot, Nadege; Park, Jong-Hyun; Phuamluong, Khanhky; Berger, Anthony L.; Park, Ki Duk; Ron, Dorit |
| 2022-12 | MAO-B Inhibitor, KDS2010, Alleviates Spinal Nerve Ligation-induced Neuropathic Pain in Rats Through Competitively Blocking the BDNF/TrkB/NR2B Signaling | Pham, Thuy Linh; Noh, Chan; Neupane, Chiranjivi; Sharma, Ramesh; Shin, Hyun Jin; Park, Ki Duk; Lee, C. Justin; Kim, Hyun-Woo; Lee, So Yeong; Park, Jin Bong |
| 2021-10 | Melatonin Analogues Potently Inhibit MAO-B and Protect PC12 Cells against Oxidative Stress | Elkamhawy, Ahmed; Woo, Jiyu; Gouda, Noha A.; Kim, Jushin; Nada, Hossam; Roh, Eun Joo; Park, Ki Duk; Cho, Jungsook; Lee, Kyeong |
| 2022-12 | Neuronal CRMP2 phosphorylation inhibition by the flavonoid, naringenin, contributes to the reversal of spinal sensitization and arthritic pain improvement | Jiang, Yue-Peng; Wang, Song; Lai, Wei-Dong; Wu, Xue-Qing; Jin, Yan; Xu, Zheng-Hao; Moutal, Aubin; Khanna, Rajesh; Park, Ki Duk; Shan, Zhi-Ming; Wen, Cheng-Ping; Yu, Jie |
| 2019-03 | Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer's disease | Park, Jong-Hyun; Ju, Yeon Ha; Choi, Ji Won; Song, Hyo Jung; Jang, Bo Ko; Woo, Junsung; Chun, Heejung; Kim, Hyeon Jeong; Shin, Su Jeong; Yarishkin, Oleg; Jo, Seonmi; Park, Mijeong; Yeon, Seul Ki; Kim, Siwon; Kim, Jeongyeon; Nam, Min-Ho; Londhe, Ashwini M.; Kim, Jina; Cho, Sung Jin; Cho, Suengmok; Lee, Changho; Hwang, Sung Yeoun; Kim, Sang Wook; Oh, Soo-Jin; Cho, Jeiwon; Pae, Ae Nim; Lee, C. Justin; Park, Ki Duk |
| 2016-02 | Novel Scaffold Identification of mGlu1 Receptor Negative Allosteric Modulators Using a Hierarchical Virtual Screening Approach | Jang, Jae Wan; Cho, Nam-Chul; Min, Sun-Joon; Cho, Yong Seo; Park, Ki Duk; Seo, Seon Hee; No, Kyoung Tai; Pae, Ae Nim |
| 2020-05 | Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal model | Kim, Siwon; Viswanath, Ambily Nath Indu; Park, Jong-Hyun; Lee, Ha Eun; Park, A. Yeong; Choi, Ji Won; Kim, Hyeon Jeong; Londhe, Ashwini M.; Jang, Bo Ko; Lee, Jaeick; Hwang, Hayoung; Lim, Sang Min; Pae, Ae Nim; Park, Ki Duk |
| 2021-11-11 | Optimization and Evaluation of Novel Antifungal Agents for the Treatment of Fungal Infection | Choi, Ji Won; Lee, Kyung-Tae; Kim, Siwon; Lee, Ye Rim; Kim, Hyeon Ji; Seo, Kyung Jin; Lee, Myung Ha; Yeon, Seul Ki; Jang, Bo Ko; Park, Sun Jun; Kim, Hyeon Jeong; Park, Jong-Hyun; Kim, Dahee; Lee, Dong-Gi; Cheong, Eunji; Lee, Jong-Seung; Bahn, Yong-Sun; Park, Ki Duk |
| 2023-08 | Optimization and evaluation of pyridinyl vinyl sulfones as Nrf2 activator for the antioxidant and anti-inflammatory effects | Kim, Byungeun; Kim, Rium; Kim, Hyeon Jeong; Kim, Yoowon; Park, Sun Jun; Lee, Elijah Hwejin; Kim, Jushin; Kim, Jaehwan; Choi, Ji Won; Park, Jong-Hyun; Park, Ki Duk |
| 2019-01 | Optimization of Vinyl Sulfone Derivatives as Potent Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Activators for Parkinson's Disease Therapy | Choi, Ji Won; Kim, Siwon; Park, Jong-Hyun; Kim, Hyeon Jeong; Shin, Su Jeon; Kim, Jin Woo; Woo, Seo Yeon; Lee, Changho; Han, Sang Moon; Lee, Jaeick; Pae, Ae Nim; Han, Gyoonhee; Park, Ki Duk |
| 2013-09-01 | Oxazolopyridines and thiazolopyridines as monoamine oxidase B inhibitors for the treatment of Parkinson's disease | Park, Hye Ri; Kim, Jiyoon; Kim, Taekeun; Jo, Seonmi; Yeom, Miyoung; Moon, Bongjin; Choo, Il Han; Lee, Jaeick; Lim, Eun Jeong; Park, Ki Duk; Min, Sun-Joon; Nam, Ghilsoo; Keum, Gyochang; Lee, C. Justin; Choo, Hyunah |
| 2019-07 | Phosphorylated CRMP2 Regulates Spinal Nociceptive Neurotransmission | Yu, Jie; Moutal, Aubin; Dorame, Angie; Bellampalli, Shreya S.; Chefdeville, Aude; Kanazawa, Iori; Pham, Nancy Y. N.; Park, Ki Duk; Weimer, Jill M.; Khanna, Rajesh |
| 2022-12 | Positional scanning of natural product hispidol's ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases | Hassan, Ahmed H. E.; Kim, Hyeon Jeong; Gee, Min Sung; Park, Jong-Hyun; Jeon, Hye Rim; Lee, Cheol Jung; Choi, Yeonwoo; Moon, Suyeon; Lee, Danbi; Lee, Jong Kil; Park, Ki Duk; Lee, Yong Sup |
| 2020-06-17 | PyrPeg, a Blood-Brain-Barrier-Penetrating Two-Photon Imaging Probe, Selectively Detects Neuritic Plaques, Not Tau Aggregates | Choi, Ji-Woo; Ju, Yeon Ha; Choi, Yunsook; Hyeon, Seung Jae; Gadhe, Changdev G.; Park, Jong-Hyun; Kim, Mun Seok; Baek, Seungyeop; Kim, YoungSoo; Park, Ki Duk; Pae, Ae Nim; Ryu, Hoon; Lee, C. Justin; Cho, Bong Rae |
| 2016-02 | Relationship between chromatographic resolution and amide structure of chiral 2-hydroxy acids as O-(-)-menthoxycarbonylated diastereomeric derivatives for enantiomeric separation on achiral gas chromatography | Cha, Eunju; Kim, Sohee; Lee, Kang Mi; Kim, Ho Jun; Kim, Ki Hun; Kwon, Oh-Seung; Park, Ki Duk; Lee, Jaeick |
| 2020-01-01 | Reprofiling of pyrimidine-based DAPK1/CSF1R dual inhibitors: identification of 2,5-diamino-4-pyrimidinol derivatives as novel potential anticancer lead compounds | Farag, Ahmed K.; Hassan, Ahmed H. E.; Ahn, Byung Sun; Park, Ki Duk; Roh, Eun Joo |
| 2016-04 | (S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5 | Moutal, Aubin; Francois-Moutal, Liberty; Perez-Miller, Samantha; Cottier, Karissa; Chew, Lindsey Anne; Yeon, Seul Ki; Dai, Jixun; Park, Ki Duk; Khanna, May; Khanna, Rajesh |
| 2016-07 | (S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology | Moutal, Aubin; Chew, Lindsey A.; Yang, Xiaofang; Wang, Yue; Yeon, Seul Ki; Telemi, Edwin; Meroueh, Seeneen; Park, Ki Duk; Shrinivasan, Raghuraman; Gilbraith, Kerry B.; Qu, Chaoling; Xie, Jennifer Y.; Patwardhan, Amol; Vanderah, Todd W.; Khanna, May; Porreca, Frank; Khanna, Rajesh |
| 2016-02-17 | Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis Optica | Ju, Eun Ji; Yeon, Seul Ki; Park, Jong-Hyun; Cheon, So Young; Choi, Ji Won; Ha, Taehwan; Jang, Bo Ko; Kim, Siwon; Kang, Yong Gu; Hwang, Hayoung; Cho, Sung Jin; Cheong, Eunji; Bahn, Yong Sun; Pae, Ae Nim; Kim, Sung Min; Park, Ki Duk |
| 2020-12 | Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H2O2- production | Chun, Heejung; Im, Hyeonjoo; Kang, You Jung; Kim, Yunha; Shin, Jin Hee; Won, Woojin; Lim, Jiwoon; Ju, Yeonha; Park, Yongmin Mason; Kim, Sunpil; Lee, Seung Eun; Lee, Jaekwang; Woo, Junsung; Hwang, Yujin; Cho, Hyesun; Jo, Seonmi; Park, Jong-Hyun; Kim, Daesoo; Kim, Doo Yeon; Seo, Jeong-Sun; Gwag, Byoung Joo; Kim, Young Soo; Park, Ki Duk; Kaang, Bong-Kiun; Cho, Hansang; Ryu, Hoon; Lee, C. Justin |
| 2014-07-24 | Substituted N-(Biphenyl-4 '-yl)methyl (R)-2-Acetamido-3-methoxypropionamides: Potent Anticonvulsants That Affect Frequency (Use) Dependence and Slow Inactivation of Sodium Channels | Lee, Hyosung; Park, Ki Duk; Torregrosa, Robert; Yang, Xiao-Fang; Dustrude, Erik T.; Wang, Yuying; Wilson, Sarah M.; Barbosa, Cindy; Xiao, Yucheng; Cummins, Theodore R.; Khanna, Rajesh; Kohn, Harold |
| 2016-08-20 | Synthesis & optimization of vinyl sulfone compounds as Nrf2 activator | Choi, Ji Won; Park, Jong Hyun; Ha, Tae Hwan; Yeon, Seul Ki; Park, Ki Duk; Kim, Si Won; Lee, Ye Rim; Shin, Su Jeong; Jang, Bo Ko |
| 2023-05 | Synthesis and Biological Evaluation of O-6-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative Diseases | Hassan, Ahmed H. E.; Kim, Hyeon Jeong; Park, Keontae; Choi, Yeonwoo; Moon, Suyeon; Lee, Chae Hyeon; Kim, Yeon Ju; Cho, Soo Bin; Gee, Min Sung; Lee, Danbi; Park, Jong-Hyun; Lee, Jong Kil; Ryu, Jong Hoon; Park, Ki Duk; Lee, Yong Sup |
| 2016-01-01 | Synthesis and biological evaluation of picolinamides and thiazole-2-carboxamides as mGluR5 (metabotropic glutamate receptor 5) antagonists | Hoang Nam Vu; Kim, Ji Young; Hassan, Ahmed H. E.; Choi, Kihang; Park, Jong-Hyun; Park, Ki Duk; Lee, Jae Kyun; Pae, Ae Nim; Choo, Hyunah; Min, Sun-Joon; Cho, Yong Seo |
| 2018-11-01 | Synthesis and Development of Novel Compounds Selectively Targeting on Sphingosine 1-Phosphate Receptor 1 (S1P1) for Treatment of Multiple Sclerosis | Yeon, Seul Ki; Park, Jong-Hyun; Park, Ki Duk; Kim, Hyeon Jeong; Shin, Su Jeong |
| 2016-08-20 | Synthesis and development of novel compounds selectively targeting on sphingosine 1-phosphate receptor 1 (S1P1) for treatment of multiple sclerosis | Yeon, Seul Ki; Park, Jong Hyun; Ha, Tae Hwan; Choi, Ji Won; Park, Ki Duk; Kim, Si Won; Lee, Ye Rim; Shin, Su Jeong; Jang, Bo Ko |
| 2018-01-01 | Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy | Yeon, Seul Ki; Choi, Ji Won; Park, Jong-Hyun; Lee, Ye Rim; Kim, Hyeon Jeong; Shin, Su Jeong; Jang, Bo Ko; Kim, Siwon; Bahn, Yong-Sun; Han, Gyoonhee; Lee, Yong Sup; Pae, Ae Nim; Park, Ki Duk |
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