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Showing results 1 to 30 of 55

Issue DateTitleAuthor(s)
2016-02A New Series of Cycloalkane-fused Coumarin Sulfonates: Synthesis and In Vitro Antiproliferative ScreeningEl-Gamal, Mohammed I.; Baek, Daejin; Oh, Chang-Hyun
2014-11-24A new series of diarylamides possessing quinoline nucleus: Synthesis, in vitro anticancer activities, and kinase inhibitory effectEl-Gamal, Mohammed I.; Khan, Mohammad Ashrafuddin; Abdel-Maksoud, Mohammed S.; El-Din, Mahmoud M. Gamal; Oh, Chang-Hyun
2017-02A Progressive Review of V600E-B-RAF-Dependent Melanoma and Drugs Inhibiting ItKhan, Mohammad Ashrafuddin; El-Gamal, Mohammed I.; Oh, Chang-Hyun
2013-09Antiproliferative Diarylpyrazole Derivatives as Dual Inhibitors of the ERK Pathway and COX-2El-Gamal, Mohammed I.; Choi, Hong Seok; Yoo, Kyung Ho; Baek, Daejin; Oh, Chang-Hyun
2016-05Broad-spectrum antiproliferative activity of a series of 6-(4-fluorophenyl)-5-(2-substituted pyrimidin-4-yl)imidazo[2,1-b]thiazole derivativesAbdel-Maksoud, Mohammed S.; El-Gamal, Mohammed I.; El-Din, Mahmoud M. Gamal; Kwak, Seong-Shin; Kim, Hyun-Il; Oh, Chang-Hyun
2014-09Cell-Based Biological Evaluation of a New Bisamide FMS Kinase Inhibitor Possessing Pyrrolo[3,2-c]pyridine ScaffoldEl-Gamal, Mohammed I.; Abdel-Maksoud, Mohammed S.; El-Din, Mahmoud M. Gamal; Yoo, Kyung Ho; Baek, Daejin; Oh, Chang-Hyun
2010-12Current Status of Carbapenem AntibioticsEl-Gamal, Mohammed I.; Oh, Chang-Hyun
2011-03-20Design and Synthesis of 3-(3-Chloro-4-substituted phenyl)-4-(pyridin-4-yl)-1H-pyrazole-1-carboxamide Derivatives and Their Antiproliferative Activity Against Melanoma Cell LineEl-Gamal, Mohammed I.; Oh, Chang-Hyun
2016-12Design and synthesis of a new series of highly potent RAF kinase-inhibiting triarylpyrazole derivatives possessing antiproliferative activity against melanoma cellsKhan, Mohammad Ashrafuddin; El-Gamal, Mohammed I.; Tarazi, Hamadeh; Choi, Hong Seok; Oh, Chang-Hyun
2012-05-20Design and Synthesis of an Anticancer Diarylurea Derivative with Multiple-Kinase Inhibitory EffectEl-Gamal, Mohammed I.; Oh, Chang-Hyun
2017-02-15Design and synthesis of new RAF kinase-inhibiting antiproliferative quinoline derivatives. Part 2: Diarylurea derivativesEl-Gamal, Mohammed I.; Khan, Mohammad Ashrafuddin; Tarazi, Hamadeh; Abdel-Maksoud, Mohammed S.; El-Din, Mahmoud M. Gamal; Yoo, Kyung Ho; Oh, Chang-Hyun
2019-12Design, synthesis, and anticancer activity of imidazo[2,1-b]oxazole-based RAF kinase inhibitorsAbdel-Maksoud, Mohammed S.; Ammar, Usama M.; El-Gamal, Mohammed I.; El-Din, Mahmoud M. Gamal; Mersal, Karim I.; Ali, Eslam M. H.; Yoo, Kyung Ho; Lee, Kyung-Tae; Oh, Chang-Hyun
2011-11Design, Synthesis, and Antiproliferative Activity of 3,4-Diarylpyrazole-1-carboxamide Derivatives Against Melanoma Cell LineEl-Gamal, Mohammed I.; Choi, Hong Seok; Cho, Hae-Guk; Hong, Jun Hee; Yoo, Kyung Ho; Oh, Chang-Hyun
2011-08Design, synthesis, and antiproliferative activity of new 1H-pyrrolo[3,2-c]pyridine derivatives against melanoma cell linesEl-Gamal, Mohammed I.; Jung, Myung-Ho; Lee, Woong San; Sim, Taebo; Yoo, Kyung Ho; Oh, Chang-Hyun
2012-07-01Design, synthesis, and antiproliferative activity of new 1H-pyrrolo[3,2-c]pyridine derivatives against melanoma cell lines. Part 2Jung, Myung-Ho; El-Gamal, Mohammed I.; Abdel-Maksoud, Mohammed S.; Sim, Taebo; Yoo, Kyung Ho; Oh, Chang-Hyun
2016-12Design, synthesis, and in vitro antiproliferative and kinase inhibitory effects of pyrimidinylpyrazole derivatives terminating with arylsulfonamido or cyclic sulfamide substituentsEl-Din, Mahmoud M. Gamal; El-Gamal, Mohammed I.; Abdel-Maksoud, Mohammed S.; Yoo, Kyung Ho; Baek, Daejin; Choi, Jungseung; Lee, Huiseong; Oh, Chang-Hyun
2012-09-20Design, Synthesis, and Preliminary Cytotoxicity Evaluation of New Diarylureas and Diarylamides Possessing 1,3,4-Triarylpyrazole ScaffoldChoi, Won-Kyoung; El-Gamal, Mohammed I.; Choi, Hong Seok; Hong, Jun Hee; Baek, Daejin; Choi, Kihang; Oh, Chang-Hyun
2011-09Design, synthesis, bioconversion, and pharmacokinetics evaluation of new ester prodrugs of olmesartanChang, Jeong-Soo; El-Gamal, Mohammed I.; Lee, Woong San; Anbar, Hanan S.; Chung, Hye Jin; Kim, Hyun-Il; Cho, Young-Jin; Lee, Bong Sang; Lee, Sun Ahe; Moon, Ji Yun; Lee, Dong Jin; Jeon, Hong-Ryeol; Lee, Jaehwi; Choi, Young Wook; Oh, Chang-Hyun
2016-08-25Design, synthesis, broad-spectrum antiproliferative activity, and kinase inhibitory effect of triarylpyrazole derivatives possessing arylamides or arylureas moietiesEl-Din, Mahmoud M. Gamal; El-Gamal, Mohammed I.; Abdel-Maksoud, Mohammed S.; Yoo, Kyung Ho; Oh, Chang-Hyun
2019-01-01Design, synthesis, in vitro anticancer evaluation, kinase inhibitory effects, and pharmacokinetic profile of new 1,3,4-triarylpyrazole derivatives possessing terminal sulfonamide moietyAbdel-Maksoud, Mohammed S.; El-Gamal, Mohammed I.; El-Din, Mahmoud M. Gamal; Oh, Chang Hyun
2015-05-05Design, synthesis, in vitro antiproliferative evaluation, and kinase inhibitory effects of a new series of imidazo[2,1-b]thiazole derivativesAbdel-Maksoud, Mohammed S.; Kim, Mi-Ryeong; El-Gamal, Mohammed I.; El-Din, Mahmoud M. Gamal; Tae, Jinsung; Choi, Hong Seok; Lee, Kyung-Tae; Yoo, Kyung Ho; Oh, Chang-Hyun
2019-01-01Design, synthesis, in vitro potent antiproliferative activity, and kinase inhibitory effects of new triarylpyrazole derivatives possessing different heterocycle terminal moietiesEl-Din, Mahmoud M. Gamal; El-Gamal, Mohammed I.; Abdel-Maksoud, Mohammed S.; Yoo, Kyung Ho; Oh, Chang-Hyun
2010-06-01Discovery of a new potent bisamide FMS kinase inhibitorEl-Gamal, Mohammed I.; Jung, Myung-Ho; Oh, Chang-Hyun
2019-02-15Discovery of highly potent V600E-B-RAF kinase inhibitors: Molecular modeling studyTarazi, Hamadeh; El-Gamal, Mohammed I.; Oh, Chang-Hyun
2013-03-01Discovery of olmesartan hexetil: A new potential prodrug of olmesartanEl-Gamal, Mohammed I.; Anbar, Hanan S.; Chung, Hye Jin; Kim, Hyun-Il; Cho, Young-Jin; Lee, Bong Sang; Lee, Sun Ahe; Moon, Ji Yun; Lee, Dong Jin; Kwon, Dow; Choi, Won-Jai; Jeon, Hong-Ryeol; Oh, Chang-Hyun
2023-12Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cellsMersal, Karim I.; Abdel-Maksoud, Mohammed S.; Ali, Eslam M. H.; Ammar, Usama M.; Zaraei, Seyed-Omar; Haque, Md Mamunul; Das, Tanuza; Hassan, Noha F.; Kim, Eunice EunKyeong; Lee, Jun-Seok; Park, Hajeung; Lee, Kwan Hyi; El-Gamal, Mohammed I.; Kim, Hee-Kwon; Ibrahim, Tamer M.; Oh, Chang-Hyun
2013-04FMS Kinase Inhibitors: Current Status and Future ProspectsEl-Gamal, Mohammed I.; Anbar, Hanan S.; Yoo, Kyung Ho; Oh, Chang-Hyun
2019-03Mechanistic/mammalian target of rapamycin: Recent pathological aspects and inhibitorsAbdel-Maksoud, Mohammed S.; El-Gamal, Mohammed I.; Benhalilou, Dalia Reyane; Ashraf, Sandy; Mohammed, Shatha Abdulghaffar; Oh, Chang-Hyun
2013-12New diarylamides and diarylureas possessing 8-amino(acetamido) quinoline scaffold: Synthesis, antiproliferative activities against melanoma cell lines, kinase inhibition, and in silico studiesKoh, Eun Jeong; El-Gamal, Mohammed I.; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Kim, Garam; Choi, Hong Seok; Hong, Jun Hee; Lee, Sang-gi; Yoo, Kyung Ho
2011-12New diarylureas and diarylamides containing 1,3,4-triarylpyrazole scaffold: Synthesis, antiproliferative evaluation against melanoma cell lines, ERK kinase inhibition, and molecular docking studiesChoi, Won-Kyoung; El-Gamal, Mohammed I.; Choi, Hong Seok; Baek, Daejin; Oh, Chang-Hyun
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