Full metadata record

DC Field Value Language
dc.contributor.authorKim, Sungwon-
dc.contributor.authorNam, Yun Sik-
dc.contributor.authorMin, Yeon Jin-
dc.contributor.authorKim, Jong-Ho-
dc.contributor.authorKim, Kwangmeyong-
dc.contributor.authorChoi, Kui Won-
dc.contributor.authorNoh, Insup-
dc.contributor.authorKwon, Ick Chan-
dc.date.accessioned2024-01-19T13:39:05Z-
dc.date.available2024-01-19T13:39:05Z-
dc.date.created2022-03-07-
dc.date.issued2007-
dc.identifier.issn1013-9826-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/116440-
dc.description.abstractStability and disintegration of natural polyelectrolyte complex microspheres for protein drugs delivery, have been extensively investigated because of their great influence on the drug release patterns. In this study, we tested stability of microspheres with alginate (Alg) core layered by either chitosan (Chi) or glycol chitosan (GChi) by examining release profiles of fluorophore-labeled bovine serum albumin (BSA) and lysozyme (Lys) from the microspheres. While GChi shell was disintegrated quickly, Chi-shell microspheres showed good stability in PBS. Disintegration of the coated layer induced the core material instable, The results indicated that while the charges of the shell material provided additional diffusion barrier against the protein release, the key factor to hold the proteins inside the microspheres was the integrity of the outer coating layer.-
dc.languageEnglish-
dc.publisherTRANS TECH PUBLICATIONS LTD-
dc.titleRelease profile of a model protein drug depending on the stability of microspheres based on polyelectrolyte complex-
dc.typeConference-
dc.identifier.doi10.4028/www.scientific.net/KEM.342-343.505-
dc.description.journalClass1-
dc.identifier.bibliographicCitation7th Asian Symposium on Biomedical Materials (ASBM7), v.342-343, pp.505 - +-
dc.citation.title7th Asian Symposium on Biomedical Materials (ASBM7)-
dc.citation.volume342-343-
dc.citation.startPage505-
dc.citation.endPage+-
dc.citation.conferencePlaceSZ-
dc.citation.conferencePlaceCheju Isl, SOUTH KOREA-
dc.citation.conferenceDate2006-08-20-
dc.relation.isPartOfASBM7: ADVANCED BIOMATERIALS VII-
dc.identifier.wosid000246657900127-
dc.identifier.scopusid2-s2.0-34147105069-
dc.type.docTypeProceedings Paper-
Appears in Collections:
KIST Conference Paper > 2007
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE