DSpace at KISTKIST Article2021

Chimeric crRNAs Retaining Activity of Cas12a with Potential to Improve Specificity

Authors
Park, Jihyun; Choi, Jaewoo; Men Thi Hoai Duong; Ahn, Hee-Chul; Hong, Seung Woo; Hwang, Gil Tae; An, Jinsu; Chung, Hak Suk; Ahn, Dae-Ro
Issue Date
2021-01
Publisher
대한화학회
Citation
Bulletin of the Korean Chemical Society, v.42, no.1, pp.87 - 90
Abstract
RNA residues in the guide region of crRNA for Cas12a can be partially replaced by DNA.
Keywords
CRISPR; CPF1; SYSTEM; ENDONUCLEASE; COMPLEX; CRISPR-Cas; Cas12a; Chimeric crRNA
ISSN
0253-2964
URI
https://pubs.kist.re.kr/handle/201004/117569
DOI
10.1002/bkcs.12109
Appears in Collections:
KIST Article > 2021
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