Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Jo, Beom-Geun | - |
dc.contributor.author | Bong, Sim-Kyu | - |
dc.contributor.author | Jegal, Jonghwan | - |
dc.contributor.author | Kim, Su-Nam | - |
dc.contributor.author | Yang, Min Hye | - |
dc.date.accessioned | 2024-01-19T17:03:57Z | - |
dc.date.available | 2024-01-19T17:03:57Z | - |
dc.date.created | 2022-01-10 | - |
dc.date.issued | 2020-07 | - |
dc.identifier.issn | 1934-578X | - |
dc.identifier.uri | https://pubs.kist.re.kr/handle/201004/118426 | - |
dc.description.abstract | The current study was undertaken to isolate and identify anti-inflammatory and antiallergic active compounds in the ethyl acetate and butanol fractions of an ethanolic extract of the aerial parts of Sid/era ehavraOsme (SCAE). A new maltol glucoside, maltol 3-(6 ''-(2-(E)-butenoyl)-glucoside) and benzoic acid, daphnoretin (a coumarin), 6 flavonoids (apigenin, genk-wanin, taxifolin, apigenin 7-O-glucoside, luteolin 7-O-sambubioside, genkwanin 5-O-glucoside), and 2 lignans (matairesinoside and lariciresinol) were isolated from SCAE by chromatographic separation. Their chemical structures were elucidated by analyzing spectroscopic data, including 1-dimensional and 2-dimensional nuclear magnetic resonance (Fig1). Maltol 3-(6 ''-(2-(E)-butenoyl)-glucoside) significandy inhibited beta-hexosaminidase release by 85.5% in immunoglobulin E and dinitrophenyl/bovine serum albumin (DNP/BSA)induced RBL-2H3 cells. Benzoic acid from S. chamaejasme inhibited beta-hexosaminidase release (by 80.2%) in IgE and DNP/BSA-induced RBI; 2H3 cells and interleukin-4 messenger ribonucleic acid expression (by 21.9% inhibition) in propidium iodide-induced RBL-2H3 cells. | - |
dc.language | English | - |
dc.publisher | SAGE PUBLICATIONS INC | - |
dc.subject | FLAVONOIDS | - |
dc.subject | COUMARINS | - |
dc.subject | ANTIHISTAMINES | - |
dc.subject | RELEASE | - |
dc.subject | EXTRACT | - |
dc.subject | ROOTS | - |
dc.title | Antiallergic Effects of Phenolic Compounds Isolated From Stellera chamaejasme on RBL-2H3 Cells | - |
dc.type | Article | - |
dc.identifier.doi | 10.1177/1934578X20942352 | - |
dc.description.journalClass | 1 | - |
dc.identifier.bibliographicCitation | NATURAL PRODUCT COMMUNICATIONS, v.15, no.7, pp.1 - 7 | - |
dc.citation.title | NATURAL PRODUCT COMMUNICATIONS | - |
dc.citation.volume | 15 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 7 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.identifier.wosid | 000555354700001 | - |
dc.identifier.scopusid | 2-s2.0-85089141612 | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | FLAVONOIDS | - |
dc.subject.keywordPlus | COUMARINS | - |
dc.subject.keywordPlus | ANTIHISTAMINES | - |
dc.subject.keywordPlus | RELEASE | - |
dc.subject.keywordPlus | EXTRACT | - |
dc.subject.keywordPlus | ROOTS | - |
dc.subject.keywordAuthor | maltol 3-O-(4 &apos | - |
dc.subject.keywordAuthor | -O-trans-2-butenoate)-beta-D-glucopyranosidex | - |
dc.subject.keywordAuthor | Stellera chamaejasme | - |
dc.subject.keywordAuthor | Interleukin-4 | - |
dc.subject.keywordAuthor | beta-hexosamididase | - |
dc.subject.keywordAuthor | RBL-2H3 cells | - |
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