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dc.contributor.authorJo, Beom-Geun-
dc.contributor.authorBong, Sim-Kyu-
dc.contributor.authorJegal, Jonghwan-
dc.contributor.authorKim, Su-Nam-
dc.contributor.authorYang, Min Hye-
dc.date.accessioned2024-01-19T17:03:57Z-
dc.date.available2024-01-19T17:03:57Z-
dc.date.created2022-01-10-
dc.date.issued2020-07-
dc.identifier.issn1934-578X-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/118426-
dc.description.abstractThe current study was undertaken to isolate and identify anti-inflammatory and antiallergic active compounds in the ethyl acetate and butanol fractions of an ethanolic extract of the aerial parts of Sid/era ehavraOsme (SCAE). A new maltol glucoside, maltol 3-(6 ''-(2-(E)-butenoyl)-glucoside) and benzoic acid, daphnoretin (a coumarin), 6 flavonoids (apigenin, genk-wanin, taxifolin, apigenin 7-O-glucoside, luteolin 7-O-sambubioside, genkwanin 5-O-glucoside), and 2 lignans (matairesinoside and lariciresinol) were isolated from SCAE by chromatographic separation. Their chemical structures were elucidated by analyzing spectroscopic data, including 1-dimensional and 2-dimensional nuclear magnetic resonance (Fig1). Maltol 3-(6 ''-(2-(E)-butenoyl)-glucoside) significandy inhibited beta-hexosaminidase release by 85.5% in immunoglobulin E and dinitrophenyl/bovine serum albumin (DNP/BSA)induced RBL-2H3 cells. Benzoic acid from S. chamaejasme inhibited beta-hexosaminidase release (by 80.2%) in IgE and DNP/BSA-induced RBI; 2H3 cells and interleukin-4 messenger ribonucleic acid expression (by 21.9% inhibition) in propidium iodide-induced RBL-2H3 cells.-
dc.languageEnglish-
dc.publisherSAGE PUBLICATIONS INC-
dc.subjectFLAVONOIDS-
dc.subjectCOUMARINS-
dc.subjectANTIHISTAMINES-
dc.subjectRELEASE-
dc.subjectEXTRACT-
dc.subjectROOTS-
dc.titleAntiallergic Effects of Phenolic Compounds Isolated From Stellera chamaejasme on RBL-2H3 Cells-
dc.typeArticle-
dc.identifier.doi10.1177/1934578X20942352-
dc.description.journalClass1-
dc.identifier.bibliographicCitationNATURAL PRODUCT COMMUNICATIONS, v.15, no.7, pp.1 - 7-
dc.citation.titleNATURAL PRODUCT COMMUNICATIONS-
dc.citation.volume15-
dc.citation.number7-
dc.citation.startPage1-
dc.citation.endPage7-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000555354700001-
dc.identifier.scopusid2-s2.0-85089141612-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryFood Science & Technology-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaFood Science & Technology-
dc.type.docTypeArticle-
dc.subject.keywordPlusFLAVONOIDS-
dc.subject.keywordPlusCOUMARINS-
dc.subject.keywordPlusANTIHISTAMINES-
dc.subject.keywordPlusRELEASE-
dc.subject.keywordPlusEXTRACT-
dc.subject.keywordPlusROOTS-
dc.subject.keywordAuthormaltol 3-O-(4 &apos-
dc.subject.keywordAuthor-O-trans-2-butenoate)-beta-D-glucopyranosidex-
dc.subject.keywordAuthorStellera chamaejasme-
dc.subject.keywordAuthorInterleukin-4-
dc.subject.keywordAuthorbeta-hexosamididase-
dc.subject.keywordAuthorRBL-2H3 cells-
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