DSpace at KIST: Structural optimization of imidazothiazole derivatives affords a new promising series as B-Raf V600E inhibitors; synthesis, in vitro assay and in silico screening

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Structural optimization of imidazothiazole derivatives affords a new promising series as B-Raf V600E inhibitors; synthesis, in vitro assay and in silico screening

Authors: Ammar, Usama M.; Abdel-Maksoud, Mohammed S.; Ali, Eslam M. H.; Mersal, Karim, I; Yoo, Kyung Ho; Oh, Chang-Hyun

Issue Date: 2020-07

Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE

Citation: BIOORGANIC CHEMISTRY, v.100

Keywords: BIOLOGICAL EVALUATION; MALIGNANT-MELANOMA; BRAF; MUTATIONS; ENCORAFENIB; VEMURAFENIB; GROWTH; AGENTS; KINASE; BIOLOGICAL EVALUATION; MALIGNANT-MELANOMA; BRAF; MUTATIONS; ENCORAFENIB; VEMURAFENIB; GROWTH; AGENTS; KINASE; anti cancer; B-Raf V600E; Imidazo[2,1-b]thiazole; In silico screening

ISSN: 0045-2068

URI: https://pubs.kist.re.kr/handle/201004/118430

DOI: 10.1016/j.bioorg.2020.103967

Appears in Collections:: KIST Article > 2020

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