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dc.contributor.authorKim, Juhyeon-
dc.contributor.authorCho, Yong Seo-
dc.contributor.authorMin, Sun-Joon-
dc.date.accessioned2024-01-20T02:34:40Z-
dc.date.available2024-01-20T02:34:40Z-
dc.date.created2021-09-05-
dc.date.issued2016-12-
dc.identifier.issn0253-2964-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/123373-
dc.description.abstractA transition-metal-free and regioselective synthesis of a series of 2-amino-4-alkoxypyrimidines is described. The SNAr alkoxylation of 2,4-dichloropyrimidines regioselectively provided 2-chloro-4-alkoxypyrimidines, which were subsequently subject to the second SNAr amination with cyclic amines in the presence of triethylamine at high temperature to afford 2-amino-4-alkoxypyrimidines in good overall yield.-
dc.languageEnglish-
dc.publisherWILEY-V C H VERLAG GMBH-
dc.subjectCROSS-COUPLING REACTIONS-
dc.subjectREGIOSELECTIVE 4-AMINO-DE-CHLORINATION-
dc.subjectHETEROCYCLES-
dc.subjectPYRIMIDINES-
dc.subjectINHIBITOR-
dc.subjectEFFICIENT-
dc.titleFacile Synthesis of 2-Amino-4-alkoxypyrimidines via Consecutive Nucleophilic Aromatic Substitution (SNAr) Reactions-
dc.typeArticle-
dc.identifier.doi10.1002/bkcs.11014-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.37, no.12, pp.1998 - 2008-
dc.citation.titleBULLETIN OF THE KOREAN CHEMICAL SOCIETY-
dc.citation.volume37-
dc.citation.number12-
dc.citation.startPage1998-
dc.citation.endPage2008-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.identifier.kciidART002172604-
dc.identifier.wosid000390270200018-
dc.identifier.scopusid2-s2.0-85003703938-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusCROSS-COUPLING REACTIONS-
dc.subject.keywordPlusREGIOSELECTIVE 4-AMINO-DE-CHLORINATION-
dc.subject.keywordPlusHETEROCYCLES-
dc.subject.keywordPlusPYRIMIDINES-
dc.subject.keywordPlusINHIBITOR-
dc.subject.keywordPlusEFFICIENT-
dc.subject.keywordAuthor2-Amino-4-alkoxypyrimidines-
dc.subject.keywordAuthorNucleophilic aromatic substitution-
dc.subject.keywordAuthorRegioselectivity-
dc.subject.keywordAuthorAlkoxylation-
dc.subject.keywordAuthorAmination-
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