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dc.contributor.authorYun, Jun-
dc.contributor.authorHan, Minsoo-
dc.contributor.authorSong, Chiman-
dc.contributor.authorCheon, Seung Hoon-
dc.contributor.authorChoi, Kihang-
dc.contributor.authorHahn, Hoh-Gyu-
dc.date.accessioned2024-01-20T09:03:59Z-
dc.date.available2024-01-20T09:03:59Z-
dc.date.created2021-09-05-
dc.date.issued2014-08-01-
dc.identifier.issn0960-894X-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/126492-
dc.description.abstractWe report the synthesis of 3-phenethylazetidine derivatives 2 and their biological activities against 5-HT, NE and DA transporters as well as microsomal stability, CYP inhibition, and hERG inhibition profiles. Compound 2at showed most potent triple reuptake inhibitor with good selectivity as a candidate for depression. (C) 2014 Elsevier Ltd. All rights reserved.-
dc.languageEnglish-
dc.publisherPergamon Press Ltd.-
dc.subjectBUPROPION-
dc.subjectCOMBINATION-
dc.titleSynthesis and biological evaluation of 3-phenethylazetidine derivatives as triple reuptake inhibitors-
dc.typeArticle-
dc.identifier.doi10.1016/j.bmcl.2014.06.026-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBioorganic & Medicinal Chemistry Letters, v.24, no.15, pp.3234 - 3237-
dc.citation.titleBioorganic & Medicinal Chemistry Letters-
dc.citation.volume24-
dc.citation.number15-
dc.citation.startPage3234-
dc.citation.endPage3237-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000339228700002-
dc.identifier.scopusid2-s2.0-84904065583-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusBUPROPION-
dc.subject.keywordPlusCOMBINATION-
dc.subject.keywordAuthorDepression-
dc.subject.keywordAuthorAntidepressant-
dc.subject.keywordAuthorTriple reuptake inhibitor-
dc.subject.keywordAuthor3-Phenethylazetidines-
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