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dc.contributor.authorKim, Seong-Hwan-
dc.contributor.authorKo, Hyeonseok-
dc.contributor.authorBang, Hea-Son-
dc.contributor.authorPark, Seon-Hui-
dc.contributor.authorKim, Dong-Gyu-
dc.contributor.authorKwon, Hak Cheol-
dc.contributor.authorKim, Sun Yeou-
dc.contributor.authorShin, Jongheon-
dc.contributor.authorOh, Dong-Chan-
dc.date.accessioned2024-01-20T16:03:58Z-
dc.date.available2024-01-20T16:03:58Z-
dc.date.created2021-09-05-
dc.date.issued2011-10-01-
dc.identifier.issn0960-894X-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/129907-
dc.description.abstractTwo new phenylpyridines, named coprismycins A and B (1 and 2), and previously reported dipyridines (3-6) were isolated from a culture of Streptomyces sp. associated with the dung beetle, Copris tripartitus. The structures of the coprismycins (1 and 2) were elucidated by the analysis of 1D and 2D NMR spectra and mass, UV, and IR spectra. Coprismycins A-B (1 and 2) and dipyridines (5 and 6) displayed comparable neuroprotective effects against MPP+ (1-methyl-4-phenylpyrimidium)-induced neurotoxicity in neuroblastoma SH-SY5Y cells. (C) 2011 Elsevier Ltd. All rights reserved.-
dc.languageEnglish-
dc.publisherPergamon Press Ltd.-
dc.subjectTYROSINE-
dc.titleCoprismycins A and B, neuroprotective phenylpyridines from the dung beetle-associated bacterium, Streptomyces sp.-
dc.typeArticle-
dc.identifier.doi10.1016/j.bmcl.2011.08.023-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBioorganic & Medicinal Chemistry Letters, v.21, no.19, pp.5715 - 5718-
dc.citation.titleBioorganic & Medicinal Chemistry Letters-
dc.citation.volume21-
dc.citation.number19-
dc.citation.startPage5715-
dc.citation.endPage5718-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000294714400010-
dc.identifier.scopusid2-s2.0-80052591205-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusTYROSINE-
dc.subject.keywordAuthorPhenylpyridine-
dc.subject.keywordAuthorNeuroprotective activity-
dc.subject.keywordAuthorDung beetle-
dc.subject.keywordAuthorCopris tripartitus-
dc.subject.keywordAuthorStreptomyces-
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