Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor

Authors
Vendrell, MarcKrishna, Gaddamanugu GopiGhosh, Krishna KantaZhai, DuantingLee, Jun-SeokZhu, QingYau, Yin HoeShochat, Susana GeifmanKim, HyoriChung, JunhoChang, Young-Tae
Issue Date
2011-08
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v.47, no.29, pp.8424 - 8426
Abstract
The diversification of the BODIPY scaffold has been hindered by its controversial adaptability to solid-phase chemistry. Herein we report the first solid-phase synthesis of a BODIPY library in high purities. We screened the library against a set of proteins, identified an immunoglobulin fluorescent sensor (Ig Orange) and confirmed its binding by SPR experiments.
Keywords
COMBINATORIAL SYNTHESIS; CYANINE DYES; FUNCTIONALIZATION; DERIVATIVES; LIBRARY; CHEMISTRY; DESIGN; PROBE; BORON; COMBINATORIAL SYNTHESIS; CYANINE DYES; FUNCTIONALIZATION; DERIVATIVES; LIBRARY; CHEMISTRY; DESIGN; PROBE; BORON; fluorescence; probe; immunoglobulin
ISSN
1359-7345
URI
https://pubs.kist.re.kr/handle/201004/130163
DOI
10.1039/c1cc11774b
Appears in Collections:
KIST Article > 2011
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