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dc.contributor.authorTanaka, Ayano-
dc.contributor.authorArai, Yasuhiro-
dc.contributor.authorKim, Su-Nam-
dc.contributor.authorHam, Jungyeob-
dc.contributor.authorUsuki, Toyonobu-
dc.date.accessioned2024-01-20T17:30:33Z-
dc.date.available2024-01-20T17:30:33Z-
dc.date.created2021-09-02-
dc.date.issued2011-04-
dc.identifier.issn1028-6020-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/130500-
dc.description.abstractConcise total synthesis of bilobol 5-pentadecenylresorcinol (1), isolated from Gingko biloba fruits, has been achieved in 10 steps with 51% overall yield from 3,5-dihydroxybenzoic acid (3). Adipostatin A (2), isolated from the fruits as well as from Streptomyces cyaneus 2299-SV1, has also been synthesized in two steps from methylated bilobol (10). The structure-activity relationship study of synthetic products was described by means of cytotoxic assay against human KB carcinoma cell lines.-
dc.languageEnglish-
dc.publisherTAYLOR & FRANCIS LTD-
dc.subjectNATURALLY-OCCURRING 5-ALKYLRESORCINOLS-
dc.subjectLONG-CHAIN PHENOLS-
dc.subjectGINKGO-BILOBA-
dc.subjectDNA-
dc.subjectINHIBITORS-
dc.titleSynthesis and biological evaluation of bilobol and adipostatin A-
dc.typeArticle-
dc.identifier.doi10.1080/10286020.2011.554828-
dc.description.journalClass1-
dc.identifier.bibliographicCitationJOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, v.13, no.4, pp.290 - 296-
dc.citation.titleJOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH-
dc.citation.volume13-
dc.citation.number4-
dc.citation.startPage290-
dc.citation.endPage296-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000289249300002-
dc.identifier.scopusid2-s2.0-79953698448-
dc.relation.journalWebOfScienceCategoryPlant Sciences-
dc.relation.journalWebOfScienceCategoryChemistry, Applied-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryPharmacology & Pharmacy-
dc.relation.journalResearchAreaPlant Sciences-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.type.docTypeArticle-
dc.subject.keywordPlusNATURALLY-OCCURRING 5-ALKYLRESORCINOLS-
dc.subject.keywordPlusLONG-CHAIN PHENOLS-
dc.subject.keywordPlusGINKGO-BILOBA-
dc.subject.keywordPlusDNA-
dc.subject.keywordPlusINHIBITORS-
dc.subject.keywordAuthorbilobol-
dc.subject.keywordAuthoradipostatin A-
dc.subject.keywordAuthortotal synthesis-
dc.subject.keywordAuthorcytotoxicity-
dc.subject.keywordAuthorstructure-activity relationship-
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