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The Antithrombotic Activity of Ethanol Extract of Lysimachia clethroides

Authors
Lee, Jung-Ok; Park, Dong Hyun; Jung, Sang Hoon; Lee, Seung-Woo; Oak, Min-Ho
Issue Date
2010-06
Publisher
KOREAN SOC APPLIED BIOLOGICAL CHEMISTRY
Citation
JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, v.53, no.3, pp.384 - 387
Abstract
We examined the effects of the ethanol extract of whole plant of Lysimachia clethroides (LCE) on antithrombotic activity. LCE signicantly inhibited collagen, ADP-induced platelet aggregation and effectively decreased the mortality rate of mice from thromboembolism. The present findings suggested that LCE may be a promising candidate of antithrombotic agent.
Keywords
THROMBOSIS; AGGREGATION; MECHANISMS; PLATELETS; ALCOHOL; DISEASE; THROMBOSIS; AGGREGATION; MECHANISMS; PLATELETS; ALCOHOL; DISEASE; Lysimachia clethroides; platelet aggregation; thromboembolism
ISSN
1738-2203
URI
https://pubs.kist.re.kr/handle/201004/131430
DOI
10.3839/jksabc.2010.060
Appears in Collections:
KIST Article > 2010
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