Extraction of mangiferin from Mahkota Dewa (Phaleria macrocarpa) using subcritical water

Authors
Kim, Wan-JooVeriansyah, BambangLee, Youn-WooKim, JaehoonKim, Jae-Duck
Issue Date
2010-05-25
Publisher
ELSEVIER SCIENCE INC
Citation
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, v.16, no.3, pp.425 - 430
Abstract
A pharmacological active component, mangiferin, was extracted from Mahkota Dewa using subcritical water extraction. The subcritical water extractions were carried out at temperatures ranging 323-423 K, pressures ranging 0.7-4.0 MPa, and extraction times ranging 1-7 h. Extraction yield of mangiferin was measured using high-performance liquid chromatography (HPLC). The extraction yield was strongly dependent on the temperature while weakly dependent on the extraction pressure. As the extraction temperature increased, the extraction mangiferin yield increased, possibly resulting from the decrease in polarity of subcritical water at higher temperature. At an optimal extraction condition of 373 K, 4.0 MPa and extraction time of 5 h, the extraction yield of mangiferin was 21.7 mg/g. This value was close to the extraction yield with methanol (25.0 mg/g) and higher than those with water (18.6 mg/g) or ethanol (13.2 mg/g) at their boiling points. (C) 2010 Published by Elsevier B.V. on behalf of The Korean Society of Industrial and Engineering Chemistry.
Keywords
SUPERCRITICAL-FLUID EXTRACTION; CARBON-DIOXIDE; TEMPERATURES; SOLUBILITY; SUPERCRITICAL-FLUID EXTRACTION; CARBON-DIOXIDE; TEMPERATURES; SOLUBILITY; Subcritical water; Mahkota Dewa; Mangiferin; Extraction
ISSN
1226-086X
URI
https://pubs.kist.re.kr/handle/201004/131439
DOI
10.1016/j.jiec.2009.08.008
Appears in Collections:
KIST Article > 2010
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