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dc.contributor.authorYang, Min Cheol-
dc.contributor.authorKwon, Hak Cheol-
dc.contributor.authorKim, Young-Joo-
dc.contributor.authorLee, Kang Ro-
dc.contributor.authorYang, Hyun Ok-
dc.date.accessioned2024-01-20T19:31:01Z-
dc.date.available2024-01-20T19:31:01Z-
dc.date.created2021-09-02-
dc.date.issued2010-05-
dc.identifier.issn0163-3864-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/131490-
dc.description.abstractTwo new polyacetylenes, oploxynes A (1) and B (2), and the known oplopandiol (3) and falcarindiol (4) were isolated from the stein of Oplopanax clams. The structures of compounds 1 and 2 were determined to be 9,10-epoxyheptadeca-4,6-diyne-3,8-diol and 10-methoxyheptadeca-4,6-diyne-3,8,9-triol, respectively, on the basis of their UV, MS, and NMR data. The absolute configurations of these compounds were determined using the modified Mosher's method and acetonide formation. Oploxyne A (1), oplopandiol (3), and falcarindiol (4) inhibited the formation of nitric oxide (NO) and prostaglandin E(2) (PGE(2)) in lipopolysaccharide (LPS)-induced murine macrophage RAW 267.7 cells.-
dc.languageEnglish-
dc.publisherAMER CHEMICAL SOC-
dc.subjectABSOLUTE-CONFIGURATION-
dc.subjectCIRSIUM-JAPONICUM-
dc.subjectDEVILS CLUB-
dc.subjectCONSTITUENTS-
dc.subjectHORRIDUS-
dc.subject(3R,8S)-FALCARINDIOL-
dc.subjectSTEREOCHEMISTRY-
dc.subjectACETYLENES-
dc.subjectCOMPOUND-
dc.subjectCELLS-
dc.titleOploxynes A and B, Polyacetylenes from the Stems of Oplopanax elatus-
dc.typeArticle-
dc.identifier.doi10.1021/np900628j-
dc.description.journalClass1-
dc.identifier.bibliographicCitationJOURNAL OF NATURAL PRODUCTS, v.73, no.5, pp.801 - 805-
dc.citation.titleJOURNAL OF NATURAL PRODUCTS-
dc.citation.volume73-
dc.citation.number5-
dc.citation.startPage801-
dc.citation.endPage805-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000278080900002-
dc.identifier.scopusid2-s2.0-77952975396-
dc.relation.journalWebOfScienceCategoryPlant Sciences-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryPharmacology & Pharmacy-
dc.relation.journalResearchAreaPlant Sciences-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.type.docTypeArticle-
dc.subject.keywordPlusABSOLUTE-CONFIGURATION-
dc.subject.keywordPlusCIRSIUM-JAPONICUM-
dc.subject.keywordPlusDEVILS CLUB-
dc.subject.keywordPlusCONSTITUENTS-
dc.subject.keywordPlusHORRIDUS-
dc.subject.keywordPlus(3R,8S)-FALCARINDIOL-
dc.subject.keywordPlusSTEREOCHEMISTRY-
dc.subject.keywordPlusACETYLENES-
dc.subject.keywordPlusCOMPOUND-
dc.subject.keywordPlusCELLS-
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KIST Article > 2010
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