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dc.contributor.authorLee, Joo Young-
dc.contributor.authorSong, Dae-Geun-
dc.contributor.authorLee, Eun Ha-
dc.contributor.authorJung, Sang Hoon-
dc.contributor.authorNho, Chu Won-
dc.contributor.authorCha, Kwang Hyun-
dc.contributor.authorPan, Cheol-Ho-
dc.date.accessioned2024-01-20T20:04:59Z-
dc.date.available2024-01-20T20:04:59Z-
dc.date.created2021-09-05-
dc.date.issued2009-12-
dc.identifier.issn1738-2203-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/131923-
dc.description.abstractAKR1B10 is a human NADPH-dependent aldo-keto reductase family 1 1310, which has been considered as a potential cancer therapeutic target. 3,5-O-Dicaffeoyl-epi-quinic acid (3,5-DCQA) was isolated from ethyl acetate fraction of Gymnaster koraiensis (Nakai) Kitam as an AKR1B10 inhibitor. 3,5-DCQA inhibited the activity of recombinant human AKR1B10 (rhAKR1B10) with its IC50 value of 1.2 mu M and its inhibition mode was uncompetitive from enzyme kinetic analysis.-
dc.languageEnglish-
dc.publisherKOREAN SOC APPLIED BIOLOGICAL CHEMISTRY-
dc.subjectKETO REDUCTASE FAMILY-1-
dc.subjectB10-
dc.subjectMEMBER-
dc.titleInhibitory Effects of 3,5-O-Dicaffeoyl-epi-quinic Acid from Gymnaster koraiensis on AKR1B10-
dc.typeArticle-
dc.identifier.doi10.3839/jksabc.2009.121-
dc.description.journalClass1-
dc.identifier.bibliographicCitationJOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, v.52, no.6, pp.731 - 734-
dc.citation.titleJOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY-
dc.citation.volume52-
dc.citation.number6-
dc.citation.startPage731-
dc.citation.endPage734-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClasskci-
dc.identifier.kciidART001412126-
dc.identifier.wosid000274066900025-
dc.relation.journalWebOfScienceCategoryFood Science & Technology-
dc.relation.journalResearchAreaFood Science & Technology-
dc.type.docTypeArticle-
dc.subject.keywordPlusKETO REDUCTASE FAMILY-1-
dc.subject.keywordPlusB10-
dc.subject.keywordPlusMEMBER-
dc.subject.keywordAuthorAKR1B10-
dc.subject.keywordAuthoraldose reductase-like-
dc.subject.keywordAuthoranticancer-
dc.subject.keywordAuthor3,5-DCQA-
dc.subject.keywordAuthor3,5-O-dicaffeoyl-epi-quinic acid-
dc.subject.keywordAuthorGymnaster koraiensis-
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