New Generation of Multifunctional Nanoparticles for Cancer Imaging and Therapy

Authors
Park, KyeongsoonLee, SeulkiKang, EunahKim, KwangmeyungChoi, KuiwonKwon, Ick Chan
Issue Date
2009-05-22
Publisher
WILEY-V C H VERLAG GMBH
Citation
ADVANCED FUNCTIONAL MATERIALS, v.19, no.10, pp.1553 - 1566
Abstract
Advances in nanotechnology have contributed to the development of novel nanoparticles that enable the tumor-specific delivery of imaging probes and therapeutic agents in cancer imaging and therapy. Nanobiotechnology combines nanotechnology with molecular imaging, which has led to the generation of new multifunctional nanoparticles for cancer imaging and therapy. Multifunctional nanoparticles hold great promise for the future of cancer treatment because they can detect the early onset of cancer in each individual patient and deliver suitable therapeutic agents to enhance therapeutic efficacy. The combination of tumor-targeted imaging and therapy in an all-in-one system provides a useful multimodal approach in the battle against cancer. Novel multifunctional nanoparticles thus offer a new avenue in the application of personalized medicine in the near future. Herein, new trends and the significance of novel multifunctional nanoparticles in cancer imaging and therapy are reviewed.
Keywords
GLYCOL CHITOSAN NANOPARTICLES; IRON-OXIDE NANOPARTICLES; SMALL INTERFERING RNA; QUANTUM DOTS; MAGNETIC NANOPARTICLES; DRUG-DELIVERY; PHASE-I; SUPERPARAMAGNETIC NANOPARTICLES; POLYMERIC NANOPARTICLES; INTRACELLULAR UPTAKE; GLYCOL CHITOSAN NANOPARTICLES; IRON-OXIDE NANOPARTICLES; SMALL INTERFERING RNA; QUANTUM DOTS; MAGNETIC NANOPARTICLES; DRUG-DELIVERY; PHASE-I; SUPERPARAMAGNETIC NANOPARTICLES; POLYMERIC NANOPARTICLES; INTRACELLULAR UPTAKE; cancer; imaging; multifunctional nanoparticles; nanotechnology; therapy
ISSN
1616-301X
URI
https://pubs.kist.re.kr/handle/201004/132481
DOI
10.1002/adfm.200801655
Appears in Collections:
KIST Article > 2009
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