DSpace at KISTKIST Article2009

Full metadata record

DC Field Value Language
dc.contributor.authorAhn, Chan Mug-
dc.contributor.authorPark, Byong-Gon-
dc.contributor.authorWoo, Ho Bum-
dc.contributor.authorHam, Jungyeob-
dc.contributor.authorShin, Woon-Seob-
dc.contributor.authorLee, Seokjoon-
dc.date.accessioned2024-01-20T21:35:33Z-
dc.date.available2024-01-20T21:35:33Z-
dc.date.created2021-09-03-
dc.date.issued2009-03-01-
dc.identifier.issn0960-894X-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/132659-
dc.description.abstractIn order to discover novel small vasodilatory molecules for potential use in the treatment of vascular disease, we tested the vasodilatation effect of two types of synthetic curcumin mimics, amide type (3) and sulfonyl amide type (4), upon the basilar artery of rabbits. In general, the sulfonyl amide type mimic (4) is more potent than the amide type (3). Curcumin (1) and compounds 12 and 20 effectively dilated the basilar artery of white rabbits. Crown Copyright (C) 2009 Published by Elsevier Ltd. All rights reserved.-
dc.languageEnglish-
dc.publisherPergamon Press Ltd.-
dc.subjectENDOTHELIN-1-INDUCED CONTRACTION-
dc.subjectMULTIDRUG-RESISTANCE-
dc.subjectRAT AORTA-
dc.subjectEFFICACY-
dc.subjectREVERSAL-
dc.subjectSAFETY-
dc.titleSynthesis of sulfonyl curcumin mimics exerting a vasodilatation effect on the basilar artery of rabbits-
dc.typeArticle-
dc.identifier.doi10.1016/j.bmcl.2009.01.019-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBioorganic & Medicinal Chemistry Letters, v.19, no.5, pp.1481 - 1483-
dc.citation.titleBioorganic & Medicinal Chemistry Letters-
dc.citation.volume19-
dc.citation.number5-
dc.citation.startPage1481-
dc.citation.endPage1483-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000263891200046-
dc.identifier.scopusid2-s2.0-60449116666-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusENDOTHELIN-1-INDUCED CONTRACTION-
dc.subject.keywordPlusMULTIDRUG-RESISTANCE-
dc.subject.keywordPlusRAT AORTA-
dc.subject.keywordPlusEFFICACY-
dc.subject.keywordPlusREVERSAL-
dc.subject.keywordPlusSAFETY-
dc.subject.keywordAuthorOrganic synthesis-
dc.subject.keywordAuthorCurcumin-
dc.subject.keywordAuthorSulfonyl curcumin mimics-
dc.subject.keywordAuthorVasodilatation-
dc.subject.keywordAuthorBasilar artery-
Appears in Collections:
KIST Article > 2009
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML
Show Simple Item Record

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE