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dc.contributor.authorChoi, Hyun-Sik-
dc.contributor.authorKim, Hyoung Ja-
dc.contributor.authorNam, Sang-Gil-
dc.contributor.authorKim, In-Seon-
dc.contributor.authorLee, Kyung-Tae-
dc.contributor.authorYook, Chang-Soo-
dc.contributor.authorLee, Yong Sup-
dc.date.accessioned2024-01-20T22:32:14Z-
dc.date.available2024-01-20T22:32:14Z-
dc.date.created2021-08-31-
dc.date.issued2008-11-
dc.identifier.issn0009-2363-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/133036-
dc.description.abstractThree new lupane-type saponins, acankoreosides F-H (1-3) were isolated from the methanol extract of the leaves of Acanthopanax koreanum NAKAI. The structures of these three saponins were established by chemical and spectroscopic analysis as 3 alpha,30-dihydroxylup-20(29)-en-23,28-dioic acid 28-O-[alpha-L-rhamnopyranosyl-(1 -> 4)-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyransoyl] ester (2), and (20S) 3 alpha-hydroxylup-23-al-28,29-dioic acid 28-O-[alpha-L-rhamnopyranosyl-(1 -> 4)-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranosyl] ester (3), respectively. The effects of the isolates (1-3) on the lipopolysaccharide-induced production of nitric oxide and prostaglandin E-2 were evaluated in RAW 264.7 macrophages.-
dc.languageEnglish-
dc.publisherPHARMACEUTICAL SOC JAPAN-
dc.subjectNFAT TRANSCRIPTION FACTOR-
dc.subjectTRITERPENE GLYCOSIDES-
dc.subjectSCHEFFLERA-OCTOPHYLLA-
dc.subjectTNF-ALPHA-
dc.subjectDITERPENOIDS-
dc.subjectSECRETION-
dc.subjectLICHENS-
dc.subjectFUNGI-
dc.subjectCELLS-
dc.subjectACID-
dc.titleLupane Glycosides from the Leaves of Acanthopanax koreanum-
dc.typeArticle-
dc.identifier.doi10.1248/cpb.56.1613-
dc.description.journalClass1-
dc.identifier.bibliographicCitationCHEMICAL & PHARMACEUTICAL BULLETIN, v.56, no.11, pp.1613 - 1616-
dc.citation.titleCHEMICAL & PHARMACEUTICAL BULLETIN-
dc.citation.volume56-
dc.citation.number11-
dc.citation.startPage1613-
dc.citation.endPage1616-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000260521600020-
dc.identifier.scopusid2-s2.0-55749085598-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalWebOfScienceCategoryPharmacology & Pharmacy-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusNFAT TRANSCRIPTION FACTOR-
dc.subject.keywordPlusTRITERPENE GLYCOSIDES-
dc.subject.keywordPlusSCHEFFLERA-OCTOPHYLLA-
dc.subject.keywordPlusTNF-ALPHA-
dc.subject.keywordPlusDITERPENOIDS-
dc.subject.keywordPlusSECRETION-
dc.subject.keywordPlusLICHENS-
dc.subject.keywordPlusFUNGI-
dc.subject.keywordPlusCELLS-
dc.subject.keywordPlusACID-
dc.subject.keywordAuthorAcanthopanax koreanum-
dc.subject.keywordAuthorAraliaceae-
dc.subject.keywordAuthorlupane glycoside-
dc.subject.keywordAuthoracankoreoside-
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