Fabrication and characterisation of CMOS compatible silicon nanowire biosensor

Authors
Kang, G. B.Park, J. M.Kim, S. G.Koo, J. G.Park, J. H.Sohn, Y. -S.Kim, Y. T.
Issue Date
2008-07-31
Publisher
INST ENGINEERING TECHNOLOGY-IET
Citation
ELECTRONICS LETTERS, v.44, no.16, pp.953 - 955
Abstract
A silicon nanowire (SiNW) biosensor for label-free and real-time detection has been fabricated by complementary metal-oxide semiconductor (CMOS) technology. For the detection of prostate-specific antigen (PSA) used as a biomarker of prostate cancer the SiNW surface was modified to immobilise the antibody of PSA (anti-PSA). Real-time monitoring reveals the change in conductivity of the SiNW on specific binding of PSA to anti-PSA. For 355 nm SiNW, the response to 10 ng/ml of PSA was 7.3%.
Keywords
DNA; DNA; nanowire; biosensor
ISSN
0013-5194
URI
https://pubs.kist.re.kr/handle/201004/133305
DOI
10.1049/el:20081876
Appears in Collections:
KIST Article > 2008
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