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dc.contributor.authorKim, Seong Jong-
dc.contributor.authorPark, Hyeong Beom-
dc.contributor.authorLee, Jae Seoung-
dc.contributor.authorJo, Nam Hyun-
dc.contributor.authorYoo, Kyung Ho-
dc.contributor.authorBaek, Daejin-
dc.contributor.authorKang, Byoung-won-
dc.contributor.authorCho, Jung-Hyuck-
dc.contributor.authorOh, Chang-Hyun-
dc.date.accessioned2024-01-21T00:33:19Z-
dc.date.available2024-01-21T00:33:19Z-
dc.date.created2021-09-02-
dc.date.issued2007-09-
dc.identifier.issn0223-5234-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/134166-
dc.description.abstractThe synthesis of a new series of 1 beta-methylcarbapenems having cyclic sulfonamide moieties is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bacteria were tested and the effect of substituent on the pyrrolidine ring was investigated. A particular compound (IIIi) having 2-methyl-[1,2,6]thiadiazinan-1, 1-dioxide moiety showed the most potent antibacterial activity. (c) 2007 Elsevier Masson SAS. All rights reserved.-
dc.languageEnglish-
dc.publisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER-
dc.subjectBETA-LACTAM ANTIBIOTICS-
dc.subjectCARBAPENEMS-
dc.subjectDERIVATIVES-
dc.titleNovel 1 beta-methylcarbapenems having cyclic sulfonamide moieties: Synthesis and evaluation of in vitro antibacterial activity-
dc.typeArticle-
dc.identifier.doi10.1016/j.ejmech.2007.02.001-
dc.description.journalClass1-
dc.identifier.bibliographicCitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.42, no.9, pp.1176 - 1183-
dc.citation.titleEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY-
dc.citation.volume42-
dc.citation.number9-
dc.citation.startPage1176-
dc.citation.endPage1183-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000249540900003-
dc.identifier.scopusid2-s2.0-34547759867-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.type.docTypeArticle-
dc.subject.keywordPlusBETA-LACTAM ANTIBIOTICS-
dc.subject.keywordPlusCARBAPENEMS-
dc.subject.keywordPlusDERIVATIVES-
dc.subject.keywordAuthor1 beta-methylcarbapenems-
dc.subject.keywordAuthorantibacterial activity-
dc.subject.keywordAuthorsubstituent effects-
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