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dc.contributor.authorJeon, Heechol-
dc.contributor.authorJo, Nam Hyun-
dc.contributor.authorYoo, Kyung Ho-
dc.contributor.authorChoi, Joung-Hoon-
dc.contributor.authorCho, Heeyeong-
dc.contributor.authorCho, Jung-Hyuck-
dc.contributor.authorOh, Chang-Hyun-
dc.date.accessioned2024-01-21T01:31:32Z-
dc.date.available2024-01-21T01:31:32Z-
dc.date.created2021-09-05-
dc.date.issued2007-03-
dc.identifier.issn0223-5234-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/134606-
dc.description.abstractThe synthesis of a new series of 1 beta-methylcarbapenems having methoxyimine and substituted sulfonamide moieties is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bacteria were tested and the effect of substituents on the pyrrolidine ring was investigated. A particular compound (IIIc) having methylaminosulfonamide moiety showed the most potent antibacterial activity. (c) 2006 Elsevier Masson SAS. All rights reserved.-
dc.languageEnglish-
dc.publisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER-
dc.subjectBETA-LACTAM ANTIBIOTICS-
dc.subjectCARBAPENEM ANTIBIOTICS-
dc.subjectTHIENAMYCIN-
dc.subject1-BETA-METHYLCARBAPENEM-
dc.subjectDERIVATIVES-
dc.titleSynthesis and antibacterial evaluation of 1 beta-methyl-2-[5-(1-methoxyimino-2-substituted sulfonamide ethyl)pyrrolidin-3-ylthio]carbapenems and their related compounds-
dc.typeArticle-
dc.identifier.doi10.1016/j.ejmech.2006.10.006-
dc.description.journalClass1-
dc.identifier.bibliographicCitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.42, no.3, pp.358 - 364-
dc.citation.titleEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY-
dc.citation.volume42-
dc.citation.number3-
dc.citation.startPage358-
dc.citation.endPage364-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000245475900008-
dc.identifier.scopusid2-s2.0-33847417058-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.type.docTypeArticle-
dc.subject.keywordPlusBETA-LACTAM ANTIBIOTICS-
dc.subject.keywordPlusCARBAPENEM ANTIBIOTICS-
dc.subject.keywordPlusTHIENAMYCIN-
dc.subject.keywordPlus1-BETA-METHYLCARBAPENEM-
dc.subject.keywordPlusDERIVATIVES-
dc.subject.keywordAuthor1 beta-methylcarbapenems-
dc.subject.keywordAuthorantibacterial activity-
dc.subject.keywordAuthorDHP-I stability-
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