The antimicrobial activity of essential oil from Dracocephalum foetidum against pathogenic microorganisms

Authors
Lee, Saet ByoulCha, Kwang HyunKim, Su NamAltantsetseg, ShatarynShatar, SanduinSarangerel, OidovsambuuNho, Chu Won
Issue Date
2007-02
Publisher
MICROBIOLOGICAL SOCIETY KOREA
Citation
JOURNAL OF MICROBIOLOGY, v.45, no.1, pp.53 - 57
Abstract
A number of essential oils from Mongolian aromatic plants are claimed to have antimicrobial activities. The essential oil of Dracocephalum foetidum, a popular essential oil used in Mongolian traditional medicine, was examined for its antimicrobial activity. Eight human pathogenic microorganisms including B. subtilis, S. aureus, M. lutens, E. hirae, S. mutans, E. coli, C. albicans, and S. cerevisiae were examined. The essential oil of Dracocephaluni foetidum exhibited strong antimicrobial activity against most of the pathogenic bacteria and yeast strains that were tested; by both the agar diffusion method and the minimum inhibitory concentration (MIC) assay (MIC range was 26-2592 mu g/ml). Interestingly, Dracocephalum foetidum even showed antimicrobial activity against methicilin-resistant Staphylococcus aureus (MRSA) strains. We also analyzed the chemical composition of the oil by GC-MS and identified several major components, including n-Mentha-1,8-dien-10-al, limonene, geranial, and neral.
Keywords
RESISTANT STAPHYLOCOCCUS-AUREUS; ANTIBACTERIAL ACTIVITY; CHEMICAL-COMPOSITION; MECHANISMS; MEMBRANE; PLANTS; RESISTANT STAPHYLOCOCCUS-AUREUS; ANTIBACTERIAL ACTIVITY; CHEMICAL-COMPOSITION; MECHANISMS; MEMBRANE; PLANTS; Dracocephalum foetidum; essential oil; antimicrobial activity; volatility; n-Mentha-1,8-dien-10-al; limonene
ISSN
1225-8873
URI
https://pubs.kist.re.kr/handle/201004/134684
Appears in Collections:
KIST Article > 2007
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