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dc.contributor.authorLee, K. S.-
dc.contributor.authorLim, J. H.-
dc.contributor.authorKang, Y. K.-
dc.contributor.authorYoo, K. H.-
dc.contributor.authorKim, D. C.-
dc.contributor.authorShin, K. J.-
dc.contributor.authorKim, D. J.-
dc.date.accessioned2024-01-21T02:04:51Z-
dc.date.available2024-01-21T02:04:51Z-
dc.date.created2021-08-31-
dc.date.issued2006-11-
dc.identifier.issn0223-5234-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/135011-
dc.description.abstractThe synthesis of new l beta-metbylcarbapenems 1a-d bearing aminopyrimidinylthioether moiety at C-5 position of pyrrolidine ring and their antibacterial activities are described. All the compounds exhibited potent antibacterial activity. Of these carbapenems, 1d showed the best combination of antibacterial activity and stability to dehydropeptidase-I (DHP-I). (c) 2006 Elsevier Masson SAS. All rights reserved.-
dc.languageEnglish-
dc.publisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER-
dc.subjectCARBAPENEM-
dc.subjectTHIENAMYCIN-
dc.titleSynthesis and antibacterial activities of new 1 beta-methylcarbapenems having aminopyrimidinylthioether moiety-
dc.typeArticle-
dc.identifier.doi10.1016/j.ejmech.2006.08.003-
dc.description.journalClass1-
dc.identifier.bibliographicCitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.41, no.11, pp.1347 - 1351-
dc.citation.titleEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY-
dc.citation.volume41-
dc.citation.number11-
dc.citation.startPage1347-
dc.citation.endPage1351-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000242454100015-
dc.identifier.scopusid2-s2.0-33750519626-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.type.docTypeArticle-
dc.subject.keywordPlusCARBAPENEM-
dc.subject.keywordPlusTHIENAMYCIN-
dc.subject.keywordAuthor1 beta-methylcarbapenems-
dc.subject.keywordAuthoraminopyrimidinylthioether-
dc.subject.keywordAuthorantibacterial activity-
dc.subject.keywordAuthorstability to DHP-I-
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