DSpace at KISTKIST Article2006

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dc.contributor.authorOh, Chang Hyun-
dc.contributor.authorHong, Joon Hee-
dc.date.accessioned2024-01-21T02:32:53Z-
dc.date.available2024-01-21T02:32:53Z-
dc.date.created2021-09-01-
dc.date.issued2006-09-
dc.identifier.issn0365-6233-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/135195-
dc.description.abstractNovel phenyl-branched cyclopropyl nucleosides, phosphonates, and phosphonic acid analogues were designed and synthesized as potential antiviral agents. Coupling of the mesylate 10 with natural bases (U, T, C, A) and desilylation/hydrolysis afforded a series of novel cyclopropyl nucleosides 15-18. Phosphonate and phosphonic acid nucleosides 22-29 were also readily synthesized from the mesylate 21. The synthesized compounds were evaluated for their antiviral activity against various viruses such as HIV-1, HSV-1, HSV-2, and HCMV.-
dc.languageEnglish-
dc.publisherWILEY-V C H VERLAG GMBH-
dc.subjectACYCLIC NUCLEOSIDES-
dc.subjectPRODRUGS-
dc.subjectANALOGS-
dc.titleSynthesis and antiviral evaluation of novel cyclopropyl nucleosides, phosphonate nucleosides and phosphonic acid nucleosides-
dc.typeArticle-
dc.identifier.doi10.1002/ardp.200600031-
dc.description.journalClass1-
dc.identifier.bibliographicCitationARCHIV DER PHARMAZIE, v.339, no.9, pp.507 - 512-
dc.citation.titleARCHIV DER PHARMAZIE-
dc.citation.volume339-
dc.citation.number9-
dc.citation.startPage507-
dc.citation.endPage512-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000240793200003-
dc.identifier.scopusid2-s2.0-33749573167-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalWebOfScienceCategoryPharmacology & Pharmacy-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusACYCLIC NUCLEOSIDES-
dc.subject.keywordPlusPRODRUGS-
dc.subject.keywordPlusANALOGS-
dc.subject.keywordAuthorantiviral agents-
dc.subject.keywordAuthorbranched nucleoside-
dc.subject.keywordAuthorcyclopropyl nucleoside, phosphonate nucleoside-
dc.subject.keywordAuthorphosphonic acid nucleoside-
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