DSpace at KISTKIST Article2003

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dc.contributor.authorLee, JS-
dc.contributor.authorCho, YS-
dc.contributor.authorChang, MH-
dc.contributor.authorKoh, HY-
dc.contributor.authorChung, BY-
dc.contributor.authorPae, AN-
dc.date.accessioned2024-01-21T08:03:07Z-
dc.date.available2024-01-21T08:03:07Z-
dc.date.created2021-09-03-
dc.date.issued2003-11-17-
dc.identifier.issn0960-894X-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/138082-
dc.description.abstractA series of isoxazolyl tetrahydropyridinyl oxazolidinones with various substituents at the 3-position of the isoxazole ring have been synthesized and their in vitro antibacterial activities (MIC) were evaluated against several Gram-positive strains including the resistant strains of Staphlyloccus and Enterococcus, such as MRSA and VRE. One of the most potent compounds synthesized, 4f, showed comparable or better activity against selected bacterial strains than those of linezolid and vancomycin. (C) 2003 Elsevier Ltd. All rights reserved.-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.titleSynthesis and in vitro activity of novel isoxazolyl tetrahydropyridinyl oxazolidinone antibacterial agents-
dc.typeArticle-
dc.identifier.doi10.1016/j.bmcl.2003.08.021-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.13, no.22, pp.4117 - 4120-
dc.citation.titleBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.citation.volume13-
dc.citation.number22-
dc.citation.startPage4117-
dc.citation.endPage4120-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000186486400050-
dc.identifier.scopusid2-s2.0-0242348685-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordAuthorisoxazolyl-
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