DSpace at KISTKIST Article2003

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dc.contributor.authorBaik, GH-
dc.contributor.authorChung, BY-
dc.contributor.authorOh, CH-
dc.contributor.authorCho, JH-
dc.contributor.authorKo, OH-
dc.contributor.authorHong, JH-
dc.date.accessioned2024-01-21T08:04:49Z-
dc.date.available2024-01-21T08:04:49Z-
dc.date.created2022-01-10-
dc.date.issued2003-11-
dc.identifier.issn1525-7770-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/138114-
dc.description.abstractA very efficient synthetic route for preparing a novel 4'-C-aryl branched-1',2'-seco-2',3'-dideoxy-2',3'-didehydro-nucleoside is described. Mesylate 7 was successfully synthesized via a Horner-Wadsworth-Emmons reaction and a [3,3]-sigmatropic rearrangement, with which an adenine base was coupled by nucleophilic substitution conditions (K2CO3, 18-Crown-6, DMF) to give the target nucleoside 9.-
dc.languageEnglish-
dc.publisherTAYLOR & FRANCIS INC-
dc.subjectHEPATITIS-B-VIRUS-
dc.subjectBIOLOGICAL EVALUATION-
dc.subjectANTIVIRAL ACTIVITY-
dc.subjectIMMUNODEFICIENCY-
dc.subjectNUCLEOTIDES-
dc.subjectTHYMIDINES-
dc.subjectANALOGS-
dc.subjectPOTENT-
dc.subjectAGENT-
dc.subjectHIV-
dc.titleNovel synthesis of 4 ' C-aryl-branched acyclic nucleoside using [3,3]-sigmatropic rearrangement-
dc.typeArticle-
dc.identifier.doi10.1081/NCN-120023272-
dc.description.journalClass1-
dc.identifier.bibliographicCitationNUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, v.22, no.9, pp.1781 - 1788-
dc.citation.titleNUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS-
dc.citation.volume22-
dc.citation.number9-
dc.citation.startPage1781-
dc.citation.endPage1788-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000185439400004-
dc.identifier.scopusid2-s2.0-0141676686-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.type.docTypeArticle-
dc.subject.keywordPlusHEPATITIS-B-VIRUS-
dc.subject.keywordPlusBIOLOGICAL EVALUATION-
dc.subject.keywordPlusANTIVIRAL ACTIVITY-
dc.subject.keywordPlusIMMUNODEFICIENCY-
dc.subject.keywordPlusNUCLEOTIDES-
dc.subject.keywordPlusTHYMIDINES-
dc.subject.keywordPlusANALOGS-
dc.subject.keywordPlusPOTENT-
dc.subject.keywordPlusAGENT-
dc.subject.keywordPlusHIV-
dc.subject.keywordAuthoracyclic nucleoside-
dc.subject.keywordAuthor[3,3]-sigmatropic rearrangement-
dc.subject.keywordAuthorantiviral agent-
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