DSpace at KISTKIST Article2003

Full metadata record

DC Field Value Language
dc.contributor.authorCha, MY-
dc.contributor.authorLee, IY-
dc.contributor.authorCha, JH-
dc.contributor.authorChoi, KI-
dc.contributor.authorCho, YS-
dc.contributor.authorKoh, HY-
dc.contributor.authorPae, AN-
dc.date.accessioned2024-01-21T09:05:03Z-
dc.date.available2024-01-21T09:05:03Z-
dc.date.created2021-09-03-
dc.date.issued2003-04-03-
dc.identifier.issn0968-0896-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/138653-
dc.description.abstractQSAR studies for piperazinylalkylisoxazole analogues were conducted by hologram QSAR (HQSAR) and comparative molecular field analysis (CoMFA) to explain the binding affinities of 264 ligands acting on dopamine D-3 receptor. The HQSAR was assessed by r(2) value of 0.917 and cross validated q(2) value of 0.841. In the CoMFA, r(2) is 0.919 and cross validated q(2) is 0.727. The results provide the tools for predicting the affinity of related compounds and guiding the design of new ligands. (C) 2003 Elsevier Science Ltd. All rights reserved.-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.titleQSAR studies on piperazinylalkyhsoxazole analogues selectively acting on dopaminie D-3 receptor by HQSAR and CoMFA-
dc.typeArticle-
dc.identifier.doi10.1016/S0968-0896(02)00617-X-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY, v.11, no.7, pp.1293 - 1298-
dc.citation.titleBIOORGANIC & MEDICINAL CHEMISTRY-
dc.citation.volume11-
dc.citation.number7-
dc.citation.startPage1293-
dc.citation.endPage1298-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000181715100015-
dc.identifier.scopusid2-s2.0-0037375828-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordAuthorQSAR-
Appears in Collections:
KIST Article > 2003
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML
Show Simple Item Record

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE