Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, DJ | - |
dc.contributor.author | Seo, KJ | - |
dc.contributor.author | Lee, KS | - |
dc.contributor.author | Shin, KJ | - |
dc.contributor.author | Yoo, KH | - |
dc.contributor.author | Kim, DC | - |
dc.contributor.author | Park, SW | - |
dc.date.accessioned | 2024-01-21T13:05:00Z | - |
dc.date.available | 2024-01-21T13:05:00Z | - |
dc.date.created | 2022-01-10 | - |
dc.date.issued | 2000-12-18 | - |
dc.identifier.issn | 0960-894X | - |
dc.identifier.uri | https://pubs.kist.re.kr/handle/201004/140837 | - |
dc.description.abstract | A new series of 1 beta -methylcarbapenems 1a-i bearing isoxazoloethenyl groups on the pyrrolidine ring has been prepared and evaluated for in vitro antibacterial activity and stability to DHP-I. Most compounds showed excellent antibacterial activity and high stability to DHP-I superior to that of meropenem. Of these new carbapenems, 1a,b,h exhibited the best combination of antibacterial activity and DHP-I stability. (C) 2000 Elsevier Science Ltd. All rights reserved. | - |
dc.language | English | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.subject | CARBAPENEM | - |
dc.title | Synthesis and biological activity of 1 beta-methyl-2-[5 '-isoxazoloethenylpyrrolidin-3 '-ylthio]carbapenems | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/S0960-894X(00)00575-8 | - |
dc.description.journalClass | 1 | - |
dc.identifier.bibliographicCitation | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.10, no.24, pp.2799 - 2802 | - |
dc.citation.title | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
dc.citation.volume | 10 | - |
dc.citation.number | 24 | - |
dc.citation.startPage | 2799 | - |
dc.citation.endPage | 2802 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.identifier.wosid | 000165849700026 | - |
dc.identifier.scopusid | 2-s2.0-0034684783 | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | CARBAPENEM | - |
dc.subject.keywordAuthor | 1 β -methylcarbapenems | - |
dc.subject.keywordAuthor | lsoxazoloethenylpyrrolidine moiety | - |
dc.subject.keywordAuthor | synthesis | - |
dc.subject.keywordAuthor | biological activity | - |
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