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dc.contributor.authorShin, KJ-
dc.contributor.authorKoo, KD-
dc.contributor.authorYoo, KH-
dc.contributor.authorKim, DC-
dc.contributor.authorKim, DJ-
dc.contributor.authorPark, SW-
dc.date.accessioned2024-01-21T13:42:17Z-
dc.date.available2024-01-21T13:42:17Z-
dc.date.created2022-01-10-
dc.date.issued2000-07-03-
dc.identifier.issn0960-894X-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/141238-
dc.description.abstractThe synthesis and biological activities of a series of new 1 beta-methylcarbapenems 1a-l having tetrazolothioether moiety at C-5 position of pyrrolidine were described. Among these compounds, 1c showed the most potent antibacterial activity and advanced pharmacokinetics compared with imipenem and meropenem. (C) 2000 Elsevier Science Ltd. All rights reserved.-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.subjectCARBAPENEMS-
dc.subjectDERIVATIVES-
dc.subjectTHIENAMYCIN-
dc.subjectC-2-
dc.titleSynthesis and biological properties of new 1 beta-methylcarbapenems having tetrazolothioether moiety-
dc.typeArticle-
dc.identifier.doi10.1016/S0960-894X(00)00253-5-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.10, no.13, pp.1421 - 1425-
dc.citation.titleBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.citation.volume10-
dc.citation.number13-
dc.citation.startPage1421-
dc.citation.endPage1425-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000087776000005-
dc.identifier.scopusid2-s2.0-0034601290-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusCARBAPENEMS-
dc.subject.keywordPlusDERIVATIVES-
dc.subject.keywordPlusTHIENAMYCIN-
dc.subject.keywordPlusC-2-
dc.subject.keywordAuthor1β-methylcarbapenems-
dc.subject.keywordAuthortetrazolothioether moiety-
dc.subject.keywordAuthorsynthesis-
dc.subject.keywordAuthorbiological properties-
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