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dc.contributor.authorKang, YK-
dc.contributor.authorShin, KJ-
dc.contributor.authorYoo, KH-
dc.contributor.authorSeo, KJ-
dc.contributor.authorHong, CY-
dc.contributor.authorLee, CS-
dc.contributor.authorPark, SY-
dc.contributor.authorKim, DJ-
dc.contributor.authorPark, SW-
dc.date.accessioned2024-01-21T14:32:48Z-
dc.date.available2024-01-21T14:32:48Z-
dc.date.created2021-09-04-
dc.date.issued2000-01-17-
dc.identifier.issn0960-894X-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/141618-
dc.description.abstractThe synthesis and biological activity of a series of new 1 beta-methylcarbapenems 1a-g containing 5'-isoxazolopyrrolidin-3'-ylthio derivatives as C-2 side chain are described. Most compounds exhibited potent and well-balanced antibacterial activity as well as high stability to DHP-1 comparable to that of meropenem. 1e and 1c showed the best combination of antibacterial activity and stability to DHP-1, respectively. (C) 2000 Elsevier Science Ltd. All rights reserved.-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.subjectDERIVATIVES-
dc.titleSynthesis and antibacterial activity of new carbapenems containing isoxazole moiety-
dc.typeArticle-
dc.identifier.doi10.1016/S0960-894X(99)00646-0-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.10, no.2, pp.95 - 99-
dc.citation.titleBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.citation.volume10-
dc.citation.number2-
dc.citation.startPage95-
dc.citation.endPage99-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000084969000002-
dc.identifier.scopusid2-s2.0-0002219569-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusDERIVATIVES-
dc.subject.keywordAuthor1β-methylcarbapenems-
dc.subject.keywordAuthorisoxazole moiety-
dc.subject.keywordAuthorSynthesis-
dc.subject.keywordAuthorbiological evaluation-
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KIST Article > 2000
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