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Radiolabeling of paclitaxel with electrophilic I-123

Authors
Roh, EJ; Park, YH; Song, CE; Oh, SJ; Choe, YS; Kim, BT; Chi, DY; Kim, DJ
Issue Date
2000-01
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Citation
BIOORGANIC & MEDICINAL CHEMISTRY, v.8, no.1, pp.65 - 68
Abstract
I-123-Labeled paclitaxel, [I-123]-1 was prepared by electrophilic aromatic radioiodination of 3'-N-(p-trimethylstannyl-benzoyl)-3'-debenzoylpaclitaxel I-123(-) in the presence of peracetic acid. (C) 2000 Elsevier Science Ltd. All rights reserved.
Keywords
TAXOL; MICROTUBULES; TAXOL; MICROTUBULES; 3 ' -N-(p-trimethylstannylbenzoyl)-3 ' -debenzoylpaclitaxel; electrophilic aromatic radioiodination; 3 ' -N-(p-[I-123]iodobenzoyl)-3 ' -debenzoylpaclitaxel; SPECT (single photon emission computed tomography)
ISSN
0968-0896
URI
https://pubs.kist.re.kr/handle/201004/141697
DOI
10.1016/S0968-0896(99)00255-2
Appears in Collections:
KIST Article > 2000
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