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Synthesis of new pyrrolidine C-nucleosides via Staudinger-aza-Wittig cyclization of gamma-azido ketone

Authors
Kim, DC; Yoo, KH; Kim, DJ; Chung, BY; Park, SW
Issue Date
1999-06-25
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Citation
TETRAHEDRON LETTERS, v.40, no.26, pp.4825 - 4828
Abstract
Novel N-acetyl C-aza-2-deoxy-D-ribonucleosides were synthesized from 2-deoxy-D-ribose via a consecutive procedure of the addition of ortho-lithiated pyrimidine salt, Staudinger-aza-Wittig ring cyclization, and reduction of cyclic imine. (C) 1999 Elsevier Science Ltd. All rights reserved.
Keywords
OLIGONUCLEOTIDES; ANALOG; HETEROCYCLES; INHIBITORS; NITROGEN; OLIGONUCLEOTIDES; ANALOG; HETEROCYCLES; INHIBITORS; NITROGEN; pyrrolidine C-nucleosides; Staudinger-aza-Wittig cyclization; gamma-azido ketone
ISSN
0040-4039
URI
https://pubs.kist.re.kr/handle/201004/142113
DOI
10.1016/S0040-4039(99)00854-0
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KIST Article > Others
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